ArticlePeerJ2019
Cloning and characterization of a tyrosine decarboxylase involved in the biosynthesis of galanthamine in
Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Amaryllidaceae Alkaloids and Isoquinoline Alkaloids: A Perspective on Historical Approaches to Pathway Elucidation.Plants (Basel, Switzerland) · 2026Review
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- Navigating Amaryllidaceae alkaloids: bridging gaps and charting biosynthetic territories.Journal of experimental botany · 2025Review
- Medicinal compounds and biotechnology of Amaryllidaceae alkaloids inFrontiers in plant science · 2025Review
- Comparative transcriptomic profiles of Paulownia catalpifolia under different degrees of chilling stress during the seedling stage.BMC genomics · 2024Article
- Functional differentiation of olive PLP_deC genes: insights into metabolite biosynthesis and genetic improvement at the whole-genome level.Plant cell reports · 2024Article
- Emerging functions within the enzyme families of plant alkaloid biosynthesis.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2023Article
- Anti-Neuroinflammatory Potential of Natural Products in the Treatment of Alzheimer's Disease.Molecules (Basel, Switzerland) · 2023Review
- Characterization of norbelladine synthase and noroxomaritidine/norcraugsodine reductase reveals a novel catalytic route for the biosynthesis of Amaryllidaceae alkaloids including the Alzheimer's drug galanthamine.Frontiers in plant science · 2023Article
- Article
- Transcriptome analysis of Leucojum aestivum and identification of genes involved in norbelladine biosynthesis.Planta · 2022Article
- Transcriptome-wide characterization of bHLH transcription factor genes inFrontiers in plant science · 2022Article
- Transcriptomic and Metabolomic Analyses Reveals That Exogenous Methyl Jasmonate Regulates Galanthamine Biosynthesis inFrontiers in plant science · 2021Article
- Biosynthesis and Biological Activities of Newly Discovered Amaryllidaceae Alkaloids.Molecules (Basel, Switzerland) · 2020Review
- Recent Progress in Amaryllidaceae Biotechnology.Molecules (Basel, Switzerland) · 2020Review
- Identification, molecular characterization and expression of JAZ genes in Lycoris aurea.PloS one · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGalanthamine, one kind of Amaryllidaceae alkaloid extracted from the
methodsBLAST was used to identify the sequence of tyrosine decarboxylase in the transcriptome of
resultsLaTYDC1 was mainly expressed in root, bulb, leaf and flower fitting the models for galanthamine accumulation. This decarboxylase efficiently catalyzes tyrosine to tyramine conversion. Under methyl jasmonate (MeJA) treatment, the expression of
conclusionLaTYDC1 participates in the biosynthesis of galanthamine, and is regulated by miR396. This finding also provides genetic strategy for improving the yield of galanthamine in the future.
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