Evidence map›Paper›PMID 31024752›Full record

ArticleActa naturae

Mauritian Endemic Medicinal Plant Extracts Induce G2/M Phase Cell Cycle Arrest and Growth Inhibition of Oesophageal Squamous Cell Carcinoma in Vitro.

N Rummun, R E Hughes, R Beesoo, W W Li, O Aldulaimi, K G Macleod, T Bahorun, N O Carragher, A Kagansky, V S Neergheen-Bhujun

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Novel assay to measure chromosome instability identifiesFrontiers in bioengineering and biotechnology · 2022
    Article
  5. Article
  6. Pharmaceuticals (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

N RummunDepartment of Health Sciences, Faculty of Science, University of Mauritius, Réduit, 80837, Republic of Mauritius.
R E HughesCancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, United Kingdom.
R BeesooDepartment of Health Sciences, Faculty of Science, University of Mauritius, Réduit, 80837, Republic of Mauritius.
W W LiGuy Hilton Research Centre, Institute for Science and Technology in Medicine, Faculty of Medicine and Health Sciences, ST5 5BG, Keele University, UK.
O AldulaimiGuy Hilton Research Centre, Institute for Science and Technology in Medicine, Faculty of Medicine and Health Sciences, ST5 5BG, Keele University, UK.
K G MacleodCancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, United Kingdom.
T BahorunANDI Centre of Excellence for Biomedical and Biomaterials Research, MSIRI Building, University of Mauritius, Réduit, 80837, Republic of Mauritius.
N O CarragherCancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, United Kingdom.
A KaganskyCancer Research UK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, United Kingdom.
V S Neergheen-BhujunDepartment of Health Sciences, Faculty of Science, University of Mauritius, Réduit, 80837, Republic of Mauritius.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Terrestrial plants have contributed massively to the development of modern oncologic drugs. Despite the wide acceptance of Mauritian endemic flowering plants in traditional medicine, scientific evidence of their chemotherapeutic potential is lacking. This study aimed to evaluate the

Indexed as

AMPKMauritian endemicmedicinal plantoesophageal carcinomatumor cytotoxicity

Identifiers

PMID31024752
PMCPMC6475868

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.