Evidence map›Paper›PMID 31024731›Full record

ArticleSAGE open medical case reports2019

Resolution of giant ocular surface squamous neoplasia with topical 5-fuorouracil 1.

Karim Mohamed-Noriega, Alan Baltazar Treviño-Herrera, Abraham Olvera-Barrios, Fernando Morales-Wong, Jesus Mohamed-Hamsho

Open access · goldAbstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Karim Mohamed-NoriegaDepartment of Ophthalmology, Faculty of Medicine, University Hospital "Dr. Jose Eleuterio Gonzalez," Autonomous University of Nuevo Leon (UANL), Monterrey, Mexico.
Alan Baltazar Treviño-HerreraDepartment of Ophthalmology, Faculty of Medicine, University Hospital "Dr. Jose Eleuterio Gonzalez," Autonomous University of Nuevo Leon (UANL), Monterrey, Mexico.
Abraham Olvera-BarriosDepartment of Ophthalmology, Faculty of Medicine, University Hospital "Dr. Jose Eleuterio Gonzalez," Autonomous University of Nuevo Leon (UANL), Monterrey, Mexico.
Fernando Morales-WongDepartment of Ophthalmology, Faculty of Medicine, University Hospital "Dr. Jose Eleuterio Gonzalez," Autonomous University of Nuevo Leon (UANL), Monterrey, Mexico.ORCID https://orcid.org/0000-0002-4836-6330
Jesus Mohamed-HamshoDepartment of Ophthalmology, Faculty of Medicine, University Hospital "Dr. Jose Eleuterio Gonzalez," Autonomous University of Nuevo Leon (UANL), Monterrey, Mexico.
Universidad Autónoma de Nuevo León · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 82-year-old man presented with a left eye elevated single ocular surface squamous neoplasia. The tumor involved 360° of limbus, three quadrants of cornea and conjunctiva; this was compatible with the diagnosis of giant ocular surface squamous neoplasia. Topical 5-fluorouracil 1% was planned four times daily for 1 week followed by 3 weeks off-treatment. Patient inadvertently continued 5-fluorouracil, four times daily for 4 weeks, presenting with clinical resolution of the ocular surface squamous neoplasia and subtotal corneal epithelial defect associated with 5-fluorouracil toxicity. One month later, we observed a transparent cornea and no signs of toxicity. Total tumor resolution was observed for at least 6 months of follow-up.

Indexed as

5-fluorouracilOcular surface squamous neoplasiaOSSN

Identifiers

PMID31024731
PMCPMC6472153
OpenAlexW2939974906

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.