ArticleFrontiers in genetics2019
Investigating Possible Trans/Intergenerational Associations With Obesity in Young Adults Using an Exposome Approach.
Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transgenerational consequences of grandparents' smoking on grandchildren's development: a systematic review.BMJ open · 2025Pooled it
- Social determinants of health influence maternal health behaviors and engagement in an obesity prevention intervention.Translational behavioral medicine · 2026Article
- Risk factors and prediction for pediatric obesity: current status and future perspectives.Endocrine journal · 2025Review
- Overweight/Obesity and Ancestral Environmental Smoking Exposures: A Summary of Results from the ALSPAC Cohort.The Yale journal of biology and medicine · 2025Article
- Fathers' preconception smoking and offspring DNA methylation.Clinical epigenetics · 2023Article
- Grandmaternal smoking during pregnancy is associated with differential DNA methylation in peripheral blood of their grandchildren.European journal of human genetics : EJHG · 2022Article
- Time to Consider the "Exposome Hypothesis" in the Development of the Obesity Pandemic.Nutrients · 2022Review
- Human transgenerational observations of regular smoking before puberty on fat mass in grandchildren and great-grandchildren.Scientific reports · 2022Article
- Regular smoking of male ancestors in adolescence and fat mass in young adult grandchildren and great-grandchildren.Wellcome open research · 2022Article
- Paternal grandmother's smoking in pregnancy is associated with extreme aversion to bitter taste in their grandchildren.Environmental epigenetics · 2022Article
- The Exposome Approach in Allergies and Lung Diseases: Is It Time to Define a Preconception Exposome?International journal of environmental research and public health · 2021Review
- Exposures during the prepuberty period and future offspring's health: evidence from human cohort studies†.Biology of reproduction · 2021Review
- Ancestral smoking and developmental outcomes: a review of publications from a population birth cohort†.Biology of reproduction · 2021Review
- An epigenetic, transgenerational model of increased mental health disorders in children, adolescents and young adults.European journal of human genetics : EJHG · 2021Review
- A butterfly flaps its wings: Extinction of biological experience and the origins of allergy.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020Review
- Epigenetic Transgenerational Inheritance of Obesity Susceptibility.Trends in endocrinology and metabolism: TEM · 2020Review
- Paternal metabolic and cardiovascular programming of their offspring: A systematic scoping review.PloS one · 2020Article
- Grandchild's IQ is associated with grandparental environments prior to the birth of the parents.Wellcome open research · 2020Article
- Attachment Patterns in Children and Adolescents With Gender Dysphoria.Frontiers in psychology · 2020Article
- Ancestral childhood environmental exposures occurring to the grandparents and great-grandparents of the ALSPAC study children.Wellcome open research · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Animal experiments demonstrate ways in which an exposure in one generation can be reflected in a variety of outcomes in later generations. In parallel human observational studies have shown associations between grandparental and parental exposures to cigarette smoking and/or nutrition and growth and survival of the grandchild. These studies have controlled for just a few confounders selected
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.