Evidence map›Paper›PMID 31024551›Full record

ReviewFrontiers in immunology2019

NKp44-NKp44 Ligand Interactions in the Regulation of Natural Killer Cells and Other Innate Lymphoid Cells in Humans.

Monica Parodi, Herman Favoreel, Giovanni Candiano, Silvia Gaggero, Simona Sivori, Maria Cristina Mingari, Lorenzo Moretta, Massimo Vitale, Claudia Cantoni

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 68 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Cytotoxic Responses Mediated by NK Cells and Cytotoxic T Lymphocytes in Xenotransplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Functional TRPA1 Channels Regulate CD56International journal of molecular sciences · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Monica ParodiImmunology Operative Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Herman FavoreelDepartment of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Giovanni CandianoLaboratory of Molecular Nephrology, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Silvia GaggeroDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Simona SivoriDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Maria Cristina MingariImmunology Operative Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Lorenzo MorettaDepartment of Immunology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Massimo VitaleImmunology Operative Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Claudia CantoniDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Ospedale Policlinico San Martino · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Genoa · ITGhent University · BEIstituto Giannina Gaslini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural Killer (NK) cells are potent cytotoxic cells belonging to the family of Innate Lymphoid Cells (ILCs). Their most characterized effector functions are directed to the control of aberrant cells in the body, including both transformed and virus-infected cells. NK cell-mediated recognition of abnormal cells primarily occurs through receptor-ligand interactions, involving an array of inhibitory and activating NK receptors and different types of ligands expressed on target cells. While most of the receptors have become known over many years, their respective ligands were only defined later and their impressive complexity has only recently become evident. NKp44, a member of Natural Cytotoxicity Receptors (NCRs), is an activating receptor playing a crucial role in most functions exerted by activated NK cells and also by other NKp44

Indexed as

AnimalsHumansImmunity, InnateKiller Cells, NaturalLigandsLymphocytesNatural Cytotoxicity Triggering Receptor 2LigandsNatural Cytotoxicity Triggering Receptor 2NCR2 protein, humaninnate lymphoid cells (ILC)ligandsnatural cytotoxicity receptors (NCR)natural kiiler cellsNKp44tumor immunologyviral infections

Identifiers

PMID31024551
PMCPMC6465645
OpenAlexW2935760763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.