Evidence map›Paper›PMID 31024518›Full record

ArticleFrontiers in immunology2019

Mycobacteria-Specific Mono- and Polyfunctional CD4+ T Cell Profiles in Children With Latent and Active Tuberculosis: A Prospective Proof-of-Concept Study.

Marc Tebruegge, Nicole Ritz, Susan Donath, Binita Dutta, Benjamin Forbes, Vanessa Clifford, Christel Zufferey, Robert De Rose, Roy M Robins-Browne, Willem Hanekom and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. ImpairedFrontiers in immunology · 2024
    Article
  2. ImmunoTargets and therapy · 2024
    Review
  3. Article
  4. Activation Phenotype ofFrontiers in immunology · 2021
    Article
  5. Article
  6. Machine Learning Algorithms Evaluate Immune Response to NovelFrontiers in cellular and infection microbiology · 2020
    Article
  7. Cell-Mediated Immune Responses toFrontiers in immunology · 2020
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Marc TebrueggeDepartment of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
Nicole RitzDepartment of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
Susan DonathDepartment of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
Binita DuttaInfectious Diseases Group, Murdoch Children's Research Institute, Parkville, VIC, Australia.
Benjamin ForbesInfectious Diseases Group, Murdoch Children's Research Institute, Parkville, VIC, Australia.
Vanessa CliffordDepartment of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
Christel ZuffereyInfectious Diseases Group, Murdoch Children's Research Institute, Parkville, VIC, Australia.
Robert De RoseDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC, Australia.
Roy M Robins-BrowneDepartment of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
Willem HanekomInstitute of Infectious Diseases and Molecular Medicine and School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
Stephen M GrahamDepartment of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
Tom ConnellDepartment of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
Nigel CurtisDepartment of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.
Murdoch Children's Research Institute · AUUniversity of Melbourne · AUGuy's and St Thomas' NHS Foundation Trust · GBPeter Doherty Institute · AUUniversity of Basel · CHUniversity of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antigens, BacterialBacterial ProteinsBiomarkersCD4-Positive T-LymphocytesCells, CulturedChildCytokinesDiagnosis, DifferentialDisease ProgressionFlow CytometryHumansImmunophenotypingLatent TuberculosisLymphocyte ActivationProof of Concept StudyProspective StudiesAntigens, BacterialBacterial ProteinsBiomarkersCFP-10 protein, Mycobacterium tuberculosisCytokinesESAT-6 protein, Mycobacterium tuberculosischilddiagnosisfunctional profileimmunoassayT celltuberculosis

Identifiers

PMID31024518
PMCPMC6459895
OpenAlexW2917947541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.