Evidence map›Paper›PMID 31024514›Full record

ArticleFrontiers in microbiology2019

Gender-Specific Associations Between Saliva Microbiota and Body Size.

Sajan C Raju, Sonja Lagström, Pekka Ellonen, Willem M de Vos, Johan G Eriksson, Elisabete Weiderpass, Trine B Rounge

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 86 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Differential effects of high-fat diet on salivary and gut microbiota.Frontiers in cellular and infection microbiology · 2025
    Article
  12. Article
  13. Review
  14. Microbiota of Saliva: A Non-invasive Diagnostic Tool.Indian journal of microbiology · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Sajan C RajuFolkhälsan Research Center, Helsinki, Finland.
Sonja LagströmInstitute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
Pekka EllonenInstitute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
Willem M de VosHuman Microbiome Research, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Johan G ErikssonFolkhälsan Research Center, Helsinki, Finland.
Elisabete WeiderpassFolkhälsan Research Center, Helsinki, Finland.
Trine B RoungeFolkhälsan Research Center, Helsinki, Finland.
University of Helsinki · FIFinland University · FIFolkhälsans Forskningscentrum · FIInstitute for Molecular Medicine Finland · FIUiT The Arctic University of Norway · NOWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe human intestinal microbiota likely play an important role in the development of overweight and obesity. However, the associations between saliva microbiota and body mass index (BMI) have been sparsely studied. The aim of this study was to identify the associations between saliva microbiota and body size in Finnish children.

methodsThe saliva microbiota of 900 Finnish children, aged 11-14 years with measured height and weight, was characterized using 16S rRNA (V3-V4) sequencing.

resultsThe core saliva microbiota consisted of 14 genera that were present in more than 95% of the Finnish children. The saliva microbiota profiles were gender-specific with higher alpha-diversity in boys than girls and significant differences between the genders in community composition and abundances. Alpha-diversity differed between normal weight and overweight girls and between normal weight and obese boys. The composition was dissimilar between normal weight and obese girls, but not in boys. The relative abundance profiles differed according to body size. Decrease in commensal saliva bacteria were observed in all the body sizes when compared to normal weight children. Notably, the relative abundance of bacteria related to,

conclusionSaliva microbiota diversity and composition were significantly associated with body size and gender in Finnish children. Body size-specific saliva microbiota profiles open new avenues for studying the potential roles of microbiota in weight development and management.

Indexed as

body mass indexchildrenmicrobiotaobesitysaliva

Identifiers

PMID31024514
PMCPMC6467948
OpenAlexW2938573248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.