ArticleFrontiers in neurology2019
Cardiac Imaging Within Emergency CT Angiography for Acute Stroke Can Detect Atrial Clots.
Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Frequency and management of non-cardiac incidental findings on cardiac CT in patients with a suspected stroke.European stroke journal · 2026Article
- Long-Term Clinical Implications of High-Risk Cardiac Computed Tomography Findings in Patients With Acute Ischemic Stroke.Journal of the American Heart Association · 2024Article
- Association between Left Atrial Appendage Morphology and Clot Histology in Patients with Embolic Ischemic Stroke: An Exploratory Study.Journal of clinical medicine · 2024Article
- Non-ECG-gated cardiac CT angiography in acute stroke is feasible and detects sources of embolism.International journal of stroke : official journal of the International Stroke Society · 2024Article
- Cardiac thrombus detected by cardiac computed tomography angiography in patients with acute ischemic stroke: a meta-analysis.Frontiers in neurology · 2024Article
- Cardiac thrombi detected by CT in patients with acute ischemic stroke: A substudy of Mind the Heart.European stroke journal · 2023Article
- Clinical outcomes following reperfusion therapy in acute ischemic stroke patients with infective endocarditis: a systematic review.Journal of central nervous system disease · 2022Review
- In Reply: Practicability and Diagnostic Yield of One-Stop Stroke CT with Delayed-Phase Cardiac CT in Detecting Major Cardioembolic Sources of Acute Ischemic Stroke.Clinical neuroradiology · 2021Article
- Cerebral Infarction Due to Aortic Mural Thrombus in a Non-atherosclerotic Ascending Aorta, Detected by Cardiac CT.NMC case report journal · 2021Article
- Deep learning reconstruction versus iterative reconstruction for cardiac CT angiography in a stroke imaging protocol: reduced radiation dose and improved image quality.Quantitative imaging in medicine and surgery · 2021Article
- Clinical Utility and Cost of Inpatient Transthoracic Echocardiography Following Acute Ischemic Stroke.The Neurohospitalist · 2021Article
- Mind the Heart: Electrocardiography-gated cardiac computed tomography-angiography in acute ischaemic stroke-rationale and study design.European stroke journal · 2020Article
- Intra-cardiac thrombus detection by electrocardiogram-gated cardiac computed tomography in hyperacute ischemic stroke.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiac embolism is presumed to cause a significant portion of cryptogenic strokes. Transesophageal echocardiography may detect intracardiac thrombi, but this remains a rare finding, possibly because remnant clots dissolve spontaneously or following thrombolysis. Cardiac imaging within cerebral CT angiography might offer an alternative method for thrombus detection within hyperacute stroke assessment. In a proof-of-concept study we analyzed records of patients aged ≥ 60 years that presented with suspected stroke and underwent extended cerebral CT angiography as part of their emergency assessment. CT imaging of patients with ischemic stroke or transient ischemic attack (TIA) and atrial fibrillation and of those with embolic strokes of undetermined source (ESUS) was reviewed for intracardiac clots and other cardiac or aortic pathology. Over a period of 3 months 59 patients underwent extended CT angiography for suspected stroke, 44 of whom received a final diagnosis of ischemic stroke or TIA. Of those, 17 had atrial fibrillation, and four fulfilled ESUS criteria. Thrombi were detected within atrial structures on CT angiography in three cases. In two ESUS patients complex atheromatosis of the proximal ascending aorta with irregular and ulcerating plaques was detected. Cardiac imaging within emergency cerebral CT angiography is feasible and can provide valuable diagnostic information in a patient group that might not routinely undergo transesophageal echocardiography. A small change to emergency assessment could potentially uncover cardioembolic pathology in cases that would have remained cryptogenic otherwise.
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