Evidence map›Paper›PMID 31024421›Full record

ReviewFrontiers in neurology2019

Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies.

Rabeea Siddique, Yang Liu, Ghulam Nabi, Wasim Sajjad, Mengzhou Xue, Suliman Khan

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Rabeea SiddiqueHenan Medical Key Laboratory of Translational Cerebrovascular Diseases, Zhengzhou University, Zhengzhou, China.
Yang LiuHenan Medical Key Laboratory of Translational Cerebrovascular Diseases, Zhengzhou University, Zhengzhou, China.
Ghulam NabiThe Key Laboratory of Aquatic Biodiversity and Conservation of Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Wasim SajjadUniversity of Chinese Academy of Sciences, Beijing, China.
Mengzhou XueHenan Medical Key Laboratory of Translational Cerebrovascular Diseases, Zhengzhou University, Zhengzhou, China.
Suliman KhanHenan Medical Key Laboratory of Translational Cerebrovascular Diseases, Zhengzhou University, Zhengzhou, China.
Second Affiliated Hospital of Zhengzhou University · CNChinese Academy of Sciences · CNInstitute of Geology and Geophysics · CNUniversity of Chinese Academy of Sciences · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the beginning of the Zika Virus (ZIKV) epidemic, thousands of cases presenting ZIKV symptoms were recorded in Brazil, Colombia (South America), French Polynesia and other countries of Central and North America. In Brazil, during ZIKV outbreak thousands of microcephaly cases occurred that caused a state of urgency among scientists and researchers to confirm the suspected association between ZIKV infection and microcephaly. In this review article we comprehensively studied scientific literature to analyze ZIKV relationship with microcephaly, recent experimental studies, challenge and shortcomings in previously published reports to know about the current status of this association. The evidences supporting the association of ZIKV infection with congenital microcephaly and fetal brain tissue damage is rapidly increasing, and supplying recent information about pathology, clinical medicine, epidemiology, mechanism and experimental studies. However, serious attention is required toward ZIKV vaccine development, standardization of anthropometric techniques, centralization of data, and advance research to clearly understand the mechanism of ZIKV infection causing microcephaly.

Indexed as

emerging infectionmicrocephalyneurological disorderspublic healthZika virus

Identifiers

PMID31024421
PMCPMC6465516
OpenAlexW2939743980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.