Evidence map›Paper›PMID 31024323›Full record

ArticleFrontiers in pharmacology2019

Cell-Free and Yeast-Based Production of the Malarial Lactate Transporter, PfFNT, Delivers Comparable Yield and Protein Quality.

Philipp Hajek, Annika Bader, Folknand Helmstetter, Björn Henke, Philipp Arnold, Eric Beitz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Philipp HajekDepartment of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian-Albrechts-University Kiel, Kiel, Germany.
Annika BaderDepartment of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian-Albrechts-University Kiel, Kiel, Germany.
Folknand HelmstetterDepartment of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian-Albrechts-University Kiel, Kiel, Germany.
Björn HenkeDepartment of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian-Albrechts-University Kiel, Kiel, Germany.
Philipp ArnoldAnatomical Institute, Christian-Albrechts-University Kiel, Kiel, Germany.
Eric BeitzDepartment of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian-Albrechts-University Kiel, Kiel, Germany.
Kiel University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-free protein production is an attractive alternative to cell-based expression. Rapid results, small-volume reactions, irrelevance of protein toxicity, flexibility, and openness of the system are strong points in favor of the cell-free system. However, the

Indexed as

biolayer interferometrycell-free protein productioninhibitor bindingL-lactatemembrane proteinPichia pastorisPlasmodium falciparumtransport

Identifiers

PMID31024323
PMCPMC6467934
OpenAlexW2938025360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.