Evidence map›Paper›PMID 31024225›Full record

ArticleFood & nutrition research2019

Chrysanthemum extract attenuates hepatotoxicity via inhibiting oxidative stress

Zixia Tian, Haiyan Jia, Yuezhen Jin, Minghui Wang, Jiejian Kou, Chunli Wang, Xuli Rong, Xinmei Xie, Guang Han, Xiaobin Pang

Open access · goldAbstract read
In one paragraph

Article in Food & nutrition research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  5. Hydrogen Protection Boosts the Bioactivity ofAntioxidants (Basel, Switzerland) · 2023
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  7. Chemical Antioxidant Quality Markers ofFrontiers in pharmacology · 2022
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  8. The genusFrontiers in plant science · 2022
    Review
  9. Article
  10. Pharmaceutical biology · 2021
    Article
  11. Nutrients · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zixia TianPharmaceutical Institute, Henan University, Kaifeng, China.
Haiyan JiaPharmaceutical Institute, Henan University, Kaifeng, China.
Yuezhen JinHenan Medical Technician Institute, Kaifeng, China.
Minghui WangPharmaceutical Institute, Henan University, Kaifeng, China.
Jiejian KouPharmaceutical Institute, Henan University, Kaifeng, China.
Chunli WangPharmaceutical Institute, Henan University, Kaifeng, China.
Xuli RongPharmaceutical Institute, Henan University, Kaifeng, China.
Xinmei XiePharmaceutical Institute, Henan University, Kaifeng, China.
Guang HanPharmaceutical Institute, Henan University, Kaifeng, China.
Xiaobin PangPharmaceutical Institute, Henan University, Kaifeng, China.
Henan University · CNHenan Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background'

objectiveIn this study, we investigated the hepatoprotective and antioxidative effects of

designSprague-Dawley rats were administered BZE by intragastric administration for 8-9 days, and then alcohol or carbon tetrachloride (CCl

resultsThe results showed that BZE prevented alcohol-, CCl

conclusionsBZE plays an important role in preventing hepatotoxicity by inhibiting oxidative stress and apoptosis through activation of Nrf2 signaling. BZE could be developed as an effective functional food for protecting the liver.

Indexed as

anti-apoptosisantioxidativechrysanthemum extractliver injurynuclear factor erythroid-2-related factor 2

Identifiers

PMID31024225
PMCPMC6475127
OpenAlexW2936389616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.