Evidence map›Paper›PMID 31023879›Full record

ArticleDevelopment (Cambridge, England)2019

Muscle precursor cell movements in zebrafish are dynamic and require Six family genes.

Jared C Talbot, Emily M Teets, Dhanushika Ratnayake, Phan Q Duy, Peter D Currie, Sharon L Amacher

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Met regulates endoderm migration in zebrafish.bioRxiv : the preprint server for biology · 2026
    Article
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  20. Anterior trunk muscle shows mix of axial and appendicular developmental patterns.Developmental dynamics : an official publication of the American Association of Anatomists · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jared C TalbotDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA talbot.39@osu.edu amacher.6@osu.edu.ORCID 0000-0001-8941-6325
Emily M TeetsDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.
Dhanushika RatnayakeAustralian Regenerative Medicine Institute, Monash University, Clayton, VIC, 3800, Australia.
Phan Q DuyDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.
Peter D CurrieAustralian Regenerative Medicine Institute, Monash University, Clayton, VIC, 3800, Australia.
Sharon L AmacherDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA talbot.39@osu.edu amacher.6@osu.edu.ORCID 0000-0002-0640-5071
Australian Regenerative Medicine Institute · AUNationwide Children's Hospital · USThe Ohio State University · US

Funding

Ohio State Neuroscience Centr CoreP30NS045758 · NINDS · OHIO STATE UNIVERSITY · PI OBRIETAN, KARL H · 2004 to 2015
$7.7M
Developmental regulation of oscillatory expressionR01GM117964 · NIGMS · OHIO STATE UNIVERSITY · PI AMACHER, SHARON L · 2015 to 2024
$2.6M
Genetic Analysis of Somitogenesis in ZebrafishR01GM061952 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI AMACHER, SHARON L · 2002 to 2011
$2.5M
Ohio State University Neuroscience Center Core-Core EP30NS104177 · NINDS · OHIO STATE UNIVERSITY · PI BROWN, ANTHONY · 2017 to 2020
$1.9M
Training in neuromuscular diseasesT32NS077984 · NINDS · OHIO STATE UNIVERSITY · PI GUTTRIDGE, DENIS C, MENDELL, JERRY ROY · 2012 to 2016
$946k
Targeted genome modification in zebrafish using zinc finger nucleasesR01GM088041 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI AMACHER, SHARON L · 2010 to 2012
$737k
A spinning disk confocal microscope for live-cell imagingS10OD010383 · OD · OHIO STATE UNIVERSITY · PI BROWN, ANTHONY · 2012 to 2012
$600k
NIGMS NIH HHS R01 GM061952NIGMS NIH HHS R01 GM088041NIGMS NIH HHS R01 GM117964NIH HHS S10 OD010383NINDS NIH HHS P30 NS045758NINDS NIH HHS P30 NS104177NINDS NIH HHS T32 NS077984
6 · The paper itself

Abstract

Muscle precursors need to be correctly positioned during embryonic development for proper body movement. In zebrafish, a subset of hypaxial muscle precursors from the anterior somites undergo long-range migration, moving away from the trunk in three streams to form muscles in distal locations such as the fin. We mapped long-distance muscle precursor migrations with unprecedented resolution using live imaging. We identified conserved genes necessary for normal precursor motility (

Indexed as

AnimalsGene Expression Regulation, DevelopmentalMuscle, SkeletalSignal TransductionSomitesZebrafishZebrafish ProteinsZebrafish ProteinsC-metLateral lineLimbPosterior hypaxial muscleSix1Six4Skeletal muscleSternohyoideusZebrafish

Identifiers

PMID31023879
PMCPMC6550023
OpenAlexW2941461257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.