Evidence map›Paper›PMID 31023846›Full record

ArticleThe European respiratory journal2019

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux.

Jeanne-Marie Perotin, James P R Schofield, Susan J Wilson, Jonathan Ward, Joost Brandsma, Fabio Strazzeri, Aruna Bansal, Xian Yang, Anthony Rowe, Julie Corfield and 29 more

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The RNA binding proteinsFrontiers in cell and developmental biology · 2023
    Article
  8. Systems Biology in Asthma.Advances in experimental medicine and biology · 2023
    Article
  9. An Overview of the Obese-Asthma Phenotype in Children.International journal of environmental research and public health · 2022
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

39 authors.

Jeanne-Marie PerotinNIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK j-m.perotin-collard@soton.ac.uk.
James P R SchofieldNIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Susan J WilsonThe Histochemistry Research Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Jonathan WardThe Histochemistry Research Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Joost BrandsmaNIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Fabio StrazzeriMathematical Sciences, University of Southampton, Southampton, UK.
Aruna BansalAcclarogen Ltd, Cambridge, UK.
Xian YangData Science Institute, Imperial College London, London, UK.
Anthony RoweJanssen Research and Development, High Wycombe, UK.
Julie CorfieldAreteva Ltd, Nottingham, UK.
Rene LutterAmsterdam UMC, Dept of Experimental Immunology (Amsterdam Infection and Immunity Institute), University of Amsterdam, Amsterdam, The Netherlands.
Dominick E ShawNIHR Biomedical Respiratory Research Centre, University of Nottingham, Nottingham, UK.ORCID 0000-0003-4106-8469
Per S BakkeInstitute of Medicine, University of Bergen, Bergen, Norway.
Massimo CarusoDept of Clinical and Experimental Medicine Hospital University, University of Catania, Catania, Italy.ORCID 0000-0002-4412-2080
Barbro DahlénDept of Respiratory Diseases and Allergy, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
Stephen J FowlerRespiratory and Allergy Research Group, University of Manchester, Manchester, UK.ORCID 0000-0002-4524-1663
Ildikó HorváthDept of Pulmonology, Semmelweis University, Budapest, Hungary.
Peter HowarthNIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Norbert KrugFraunhofer Institute for Toxicology and Experimental Medicine Hannover, Hannover, Germany.
Paolo MontuschiFaculty of Medicine, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario, Agostino Gemelli IRCCS, Rome, Italy.
Marek SanakLaboratory of Molecular Biology and Clinical Genetics, Medical College, Jagiellonian University, Krakow, Poland.
Thomas SandströmDept of Medicine, Dept of Public Health and Clinical Medicine Respiratory Medicine Unit, Umeå University, Umeå, Sweden.
Kai SunJanssen Research and Development, High Wycombe, UK.
Ioannis PandisJanssen Research and Development, High Wycombe, UK.
Charles AuffrayEuropean Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Université de Lyon, Lyons, France.
Bertrand De MeulderEuropean Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Université de Lyon, Lyons, France.
Diane LefaudeuxEuropean Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Université de Lyon, Lyons, France.ORCID 0000-0001-7075-5781
John H RileyRespiratory Therapeutic Unit, GSK, Uxbridge, UK.
Ana R SousaRespiratory Therapeutic Unit, GSK, Uxbridge, UK.
Sven-Erik DahlenThe Centre for Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Ian M AdcockCell and Molecular Biology Group, Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK.
Kian Fan ChungCell and Molecular Biology Group, Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK.
Peter J SterkNIHR Biomedical Respiratory Research Centre, University of Nottingham, Nottingham, UK.
Paul J SkippCentre for Proteomic Research, Biological Sciences, University of Southampton, Southampton, UK.
Jane E CollinsNIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Donna E DaviesNIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Ratko DjukanovićNIHR Southampton Biomedical Research Centre, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
U-BIOPRED Study Group
U-BIOPRED:

Funding

European Research Council 789384
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaCase-Control StudiesCCN Intercellular Signaling ProteinsEndoscopy, GastrointestinalEpitheliumGastroesophageal RefluxGene ExpressionHumansObesityProto-Oncogene ProteinsCCN4 protein, humanCCN Intercellular Signaling ProteinsProto-Oncogene Proteins

Identifiers

PMID31023846
PMCPMC7610816

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.