Evidence map›Paper›PMID 31023834›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Spontaneous Cingulate High-Current Spikes Signal Normal and Pathological Pain States.

Hsi-Chien Shih, Jenq-Wei Yang, Chia-Ming Lee, Bai-Chuang Shyu

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. The P2X7 Hypothesis of Central Post-Stroke Pain.International journal of molecular sciences · 2024
    Article
  2. Article
  3. Article
  4. Thalamocortical Mechanisms for Nostalgia-Induced Analgesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  5. Brain circuits for pain and its treatment.Science translational medicine · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Hsi-Chien ShihInstitute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan, Republic of China.
Jenq-Wei YangInstitute of Physiology, University Medical Center of the Johannes Gutenberg, University Mainz, D-55128 Mainz, Germany.
Chia-Ming LeeResearch Center for Applied Sciences, Academia Sinica, Taipei, 11529, Taiwan, Republic of China.
Bai-Chuang ShyuInstitute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan, Republic of China, bmbai@gate.sinica.edu.tw.ORCID 0000-0001-5619-2281
Institute of Biomedical Sciences, Academia Sinica · TWJohannes Gutenberg University Mainz · DEResearch Center for Applied Science, Academia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prominent 7-12 Hz oscillations in frontal cortical networks in rats have been reported. However, the mechanism of generation and the physiological function of this brain rhythm have not yet been clarified. Multichannel extracellular field potentials of the ACC were recorded and analyzed using the current source density method in halothane-anesthetized rats. Spontaneous high-current spikes (HCSs) were localized in the deep part of layer II/III and upper part of layer V of the ACC. The frequency of HCSs in the ACC was 7-12 Hz, with an amplitude of 6.5 ± 0.76 mV/mm

Indexed as

Action PotentialsAnalgesics, OpioidAnimalsGyrus CinguliMaleMorphineNeuronsPainRatsRats, Sprague-DawleyAnalgesics, OpioidMorphineanterior cingulate cortexbrain oscillationcentral poststroke paincurrent source densitymedial thalamusmorphine

Identifiers

PMID31023834
PMCPMC6595960
OpenAlexW2942361153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.