Evidence map›Paper›PMID 31023825›Full record

ArticleThe Journal of biological chemistry2019

Interaction of the late endo-lysosomal lipid PI(3,5)P2 with the Vph1 isoform of yeast V-ATPase increases its activity and cellular stress tolerance.

Subhrajit Banerjee, Kaitlyn Clapp, Maureen Tarsio, Patricia M Kane

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 65 citations in OpenAlex.

  1. Quantitative comparison of PI(3,5)PMolecular biology of the cell · 2026
    Article
  2. Article
  3. Article
  4. Subcellular Cartography of the Phosphoinositide Multiverse.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2026
    Review
  5. Article
  6. Quantitative comparison of PI(3,5)PbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
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  14. Review
  15. Article
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  18. Review
  19. Review
  20. Coordinated conformational changes in the VNature structural & molecular biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Subhrajit BanerjeeFrom the Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York 13210.ORCID 0000-0003-1474-8864
Kaitlyn ClappFrom the Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York 13210.
Maureen TarsioFrom the Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York 13210.
Patricia M KaneFrom the Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, New York 13210 kanepm@upstate.edu.
SUNY Upstate Medical University · US

Funding

SUBUNIT STRUCTURE/FUNCTION IN VACUOLAR H+ ATPASESR01GM050322 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI KANE, PATRICIA M · 1994 to 2015
$4.1M
Regulation of V-ATPases by PhosphoinositidesR01GM126020 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI KANE, PATRICIA M · 2018 to 2021
$1.1M
NIGMS NIH HHS R01 GM050322NIGMS NIH HHS R01 GM126020
6 · The paper itself

Abstract

The low-level endo-lysosomal signaling lipid, phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2), is required for full assembly and activity of vacuolar H

Indexed as

Amino Acid SequenceMutagenesisOsmotic PressurePhosphatidylinositol PhosphatesProtein BindingProtein IsoformsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsVacuolar Proton-Translocating ATPasesVacuolesphosphatidylinositol 3,5-diphosphatePhosphatidylinositol PhosphatesProtein IsoformsSaccharomyces cerevisiae ProteinsVacuolar Proton-Translocating ATPasesacidificationlysosomeosmoregulationosmotic stressphosphatidylinositol 3,5-bisphosphatephosphatidylinositol signalingproton pumpSaccharomyces cerevisiaevacuolar ATPasevacuole

Identifiers

PMID31023825
PMCPMC6556579
OpenAlexW2941102699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.