ArticleBMJ open2019
Identifying the lifetime cognitive and socioeconomic antecedents of cognitive state: seven decades of follow-up in a British birth cohort study.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Contribution of accumulative affective problems across the life course towards the association of childhood socioeconomic position with later-life cognitive ageing.European journal of ageing · 2026Article
- Associations between Diet Quality and Global Cognitive Ability across the Life Course: Longitudinal Analysis of the 1946 British Birth Cohort.Current developments in nutrition · 2026Article
- Persistent financial adversity and cognitive aging: a life course investigation.Innovation in aging · 2026Article
- Social Drivers of Health and Cognition in Cirrhosis: A Scoping Review.Clinical nursing research · 2025Article
- The impact of early childhood adversity on adult cognitive performance: The mediating roles of childhood cognitive ability and educational attainment.Social science & medicine (1982) · 2025Article
- High School Curricular Rigor and Cognitive Function among White Older Adults.Journal of health and social behavior · 2025Article
- Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults.Brain : a journal of neurology · 2025Article
- The multiple mediating roles of depression and grandchild care in the relationship between social participation and cognitive function among middle-aged and elderly Chinese: an empirical study based on CHARLS 2020 data.Frontiers in aging neuroscience · 2025Article
- Associations Between Midlife Anticholinergic Medication Use and Subsequent Cognitive Decline: A British Birth Cohort Study.Drugs & aging · 2024Article
- Cross-national comparisons of later-life cognitive function using data from the Harmonized Cognitive Assessment Protocol (HCAP): Considerations and recommended best practices.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Article
- Timing of physical activity across adulthood on later-life cognition: 30 years follow-up in the 1946 British birth cohort.Journal of neurology, neurosurgery, and psychiatry · 2023Article
- Adulthood cognitive trajectories over 26 years and brain health at 70 years of age: findings from the 1946 British Birth Cohort.Neurobiology of aging · 2023Article
- The Power of Birth Cohorts to Study Risk Factors for Cognitive Impairment.Current neurology and neuroscience reports · 2022Review
- Moderating Role of Cognitive Reserve Markers Between Childhood Cognition and Cognitive Aging: Evidence From the 1946 British Birth Cohort.Neurology · 2022Article
- Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study.The lancet. Healthy longevity · 2022Article
- Cognitive impairment and World Trade Centre-related exposures.Nature reviews. Neurology · 2022Review
- Metabolic correlates of late midlife cognitive outcomes: findings from the 1946 British Birth Cohort.Brain communications · 2022Article
- Childhood reading problems and cognitive ageing across mid to later life.Journal of epidemiology and community health · 2022Article
- Dissociable effects ofNature aging · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectivesThe life course determinants of midlife and later life cognitive function have been studied using longitudinal population-based cohort data, but far less is known about whether the pattern of these pathways is similar or distinct for clinically relevant cognitive state. We investigated this for Addenbrooke's Cognitive Examination third edition (ACE-III), used in clinical settings to screen for cognitive impairment and dementia.
designLongitudinal birth cohort study.
settingResidential addresses in England, Wales and Scotland.
participants1762 community-dwelling men and women of European heritage, enrolled since birth in the Medical Research Council (MRC) National Survey of Health and Development (the British 1946 birth cohort). PRIMARY OUTCOME: ACE-III.
resultsPath modelling estimated direct and indirect associations between apolipoprotein E (
conclusionsThe ACE-III in the general population shows a pattern of life course antecedents that is similar to neuropsychological measures of cognitive function, and may be used to represent normal cognitive ageing as well as a screen for cognitive impairment and dementia.
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