Evidence map›Paper›PMID 31023724›Full record

ArticleThe Journal of cell biology2019

Engineered SUMO/protease system identifies Pdr6 as a bidirectional nuclear transport receptor.

Arturo Vera Rodriguez, Steffen Frey, Dirk Görlich

Open access · hybridAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. CAD-C: An engineered nuclease enables repair-freebioRxiv : the preprint server for biology · 2026
    Article
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  3. eIF5A coordinates the transcription and translation of its target genes.Cellular and molecular life sciences : CMLS · 2026
    Article
  4. Structural evolution of the MTCH family of mitochondrial insertases.bioRxiv : the preprint server for biology · 2026
    Article
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  13. The structural basis for RNA slicing by human Argonaute2.bioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Arturo Vera RodriguezDepartment of Cellular Logistics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.ORCID 0000-0002-9217-9460
Steffen FreyDepartment of Cellular Logistics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Dirk GörlichDepartment of Cellular Logistics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany goerlich@mpibpc.mpg.de.ORCID 0000-0002-4343-5210
Max Planck Institute for Biophysical Chemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cleavage of affinity tags by specific proteases can be exploited for highly selective affinity chromatography. The SUMO/SENP1 system is the most efficient for such application but fails in eukaryotic expression because it cross-reacts with endogenous proteases. Using a novel selection system, we have evolved the SUMO

Indexed as

Active Transport, Cell NucleusAmino Acid SequenceAnimalsbeta KaryopherinsCell NucleusCysteine EndopeptidasesEukaryotic Translation Initiation Factor 5AHEK293 CellsHumansPeptide Initiation FactorsProtein BindingRNA-Binding ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence HomologySmall Ubiquitin-Related Modifier Proteinsbeta KaryopherinsCysteine EndopeptidasesEukaryotic Translation Initiation Factor 5AKAP122 protein, S cerevisiaePeptide Initiation FactorsRNA-Binding ProteinsSaccharomyces cerevisiae ProteinsSENP1 protein, humanSmall Ubiquitin-Related Modifier ProteinsUbiquitin-Conjugating Enzymes

Identifiers

PMID31023724
PMCPMC6548132
OpenAlexW2942369049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.