Evidence map›Paper›PMID 31023663›Full record

ArticleAJNR. American journal of neuroradiology2019

Intravoxel Incoherent Motion MR Imaging of Pediatric Intracranial Tumors: Correlation with Histology and Diagnostic Utility.

K Kikuchi, A Hiwatashi, O Togao, K Yamashita, R Kamei, D Momosaka, N Hata, K Iihara, S O Suzuki, T Iwaki and 1 more

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  6. Advanced MR Techniques for Preoperative Glioma Characterization: Part 1.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  7. Article
  8. Article
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  10. Perfusion-driven Intravoxel Incoherent Motion (IVIM) MRI in Oncology: Applications, Challenges, and Future Trends.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2021
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

K KikuchiFrom the Departments of Clinical Radiology (K.K., A.H., O.T., K.Y., R.K., D.M., H.H.).ORCID 0000-0003-1292-1846
A HiwatashiFrom the Departments of Clinical Radiology (K.K., A.H., O.T., K.Y., R.K., D.M., H.H.) hiwatasi@radiol.med.kyushu-u.ac.jp.ORCID 0000-0001-5400-5083
O TogaoFrom the Departments of Clinical Radiology (K.K., A.H., O.T., K.Y., R.K., D.M., H.H.).ORCID 0000-0002-5910-7852
K YamashitaFrom the Departments of Clinical Radiology (K.K., A.H., O.T., K.Y., R.K., D.M., H.H.).ORCID 0000-0002-7417-739X
R KameiFrom the Departments of Clinical Radiology (K.K., A.H., O.T., K.Y., R.K., D.M., H.H.).ORCID 0000-0003-0971-3448
D MomosakaFrom the Departments of Clinical Radiology (K.K., A.H., O.T., K.Y., R.K., D.M., H.H.).ORCID 0000-0002-9846-8693
N HataNeurosurgery (N.H., K.I.).ORCID 0000-0002-5523-7166
K IiharaNeurosurgery (N.H., K.I.).ORCID 0000-0002-7852-220X
S O SuzukiNeuropathology (S.O.S., T.I.), Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID 0000-0002-0742-5680
T IwakiNeuropathology (S.O.S., T.I.), Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID 0000-0001-7826-870X
H HondaFrom the Departments of Clinical Radiology (K.K., A.H., O.T., K.Y., R.K., D.M., H.H.).ORCID 0000-0001-8704-3078
Kia Motors (South Korea) · KRKyushu University · JPNorwegian Womens Public Health Association · NOKindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIntravoxel incoherent motion imaging, which simultaneously measures diffusion and perfusion parameters, is promising for brain tumor grading. However, intravoxel incoherent motion imaging has not been tested in children. The purpose of this study was to evaluate the correlation between intravoxel incoherent motion parameters and histology to assess the accuracy of intravoxel incoherent motion imaging for pediatric intracranial tumor grading. MATERIALS AND

methodsBetween April 2013 and September 2015, 17 children (11 boys, 6 girls; 2 months to 15 years of age) with intracranial tumors were included in this retrospective study. Intravoxel incoherent motion parameters were fitted using 13 b-values for a biexponential model. The perfusion-free diffusion coefficient, pseudodiffusion coefficient, and perfusion fraction were measured in high- and low-grade tumors. These intravoxel incoherent motion parameters and the ADC were compared using the unpaired

resultsThe perfusion-free diffusion coefficient and ADC were lower in high-grade than in low-grade tumors (perfusion-free diffusion coefficient, 0.85 ± 0.40 versus 1.53 ± 0.21 × 10

conclusionsIntravoxel incoherent motion imaging reflects tumor histology and may be a helpful, noninvasive method for pediatric intracranial tumor grading.

Indexed as

AdolescentBrain NeoplasmsChildChild, PreschoolDiffusion Magnetic Resonance ImagingFemaleHumansImage Interpretation, Computer-AssistedInfantMaleMotionNeoplasm GradingNeuroimagingRetrospective Studies

Identifiers

PMID31023663
PMCPMC7053913
OpenAlexW2941722607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.