ArticleNeuron2019
Grid-like Neural Representations Support Olfactory Navigation of a Two-Dimensional Odor Space.
Article in Neuron, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
79 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Olfactory spatial memory: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- The hippocampus as a generative model.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- An abstract relational map emerges in the human medial prefrontal cortex with consolidation.Current biology : CB · 2026Article
- Computational origins of cortical brain circuits for social cognition.Nature reviews. Neuroscience · 2026Review
- Neural population geometry and optimal coding of tasks with shared latent structure.Nature neuroscience · 2026Article
- Brain Bases for Navigating Acoustic Features.Human brain mapping · 2026Article
- Flexible neural representations of abstract structural knowledge in the human entorhinal cortex.eLife · 2026Article
- Article
- Map-like representations of emotion knowledge in hippocampal-prefrontal systems.Nature communications · 2026Article
- GHSRs in the olfactory bulb suppress food motivation and promote exploration without altering spatial memory in male mice.Journal of neuroendocrinology · 2025Article
- Cognitive Maps in the Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Predictive encoding of auditory sequences in the human prefrontal cortex.bioRxiv : the preprint server for biology · 2025Article
- Article
- Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes.Nature communications · 2025Article
- Thinking as Analogy-Making: Toward a Neural Process Account of General Intelligence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- A unified neural representation model for spatial and conceptual computations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A framework for uniting space and time in the mind and brain.Frontiers in cognition · 2025Article
- Category boundaries modulate memory in a place-cell-like manner.Current biology : CB · 2024Article
- Neural circuits for goal-directed navigation across species.Trends in neurosciences · 2024Review
- Cognitive Maps for a Non-Euclidean Environment: Path Integration and Spatial Memory on a Sphere.Psychological science · 2024Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Searching for food, friends, and mates often begins with an airborne scent. Importantly, odor concentration rises with physical proximity to an odorous source, suggesting a framework for orienting within olfactory landscapes to optimize behavior. Here, we created a two-dimensional odor space composed purely of odor stimuli to model how a navigator encounters smells in a natural environment. We show that human subjects can learn to navigate in olfactory space and form predictions of to-be-encountered smells. During navigation, fMRI responses in entorhinal cortex and ventromedial prefrontal cortex take the form of grid-like representations with hexagonal periodicity and entorhinal grid strength scaled with behavioral performance across subjects. The identification of olfactory grid-like codes with 6-fold symmetry highlights a unique neural mechanism by which odor information can be assembled into spatially navigable cognitive maps, optimizing orientation, and path finding toward an odor source.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.