ReviewJournal of medical case reports2019
Distal renal tubular acidosis and severe hypokalemia: a case report and review of the literature.
Review in Journal of medical case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Recurrent Hypokalemic Paralysis as the Initial Presentation of Primary Sjögren's Syndrome.Cureus · 2026Article
- Rare Manifestation of Sjogren's Syndrome: Renal Tubular Acidosis-Induced Hypokalemic Paralysis-A Case Report.Clinical case reports · 2026Article
- A Comprehensive Approach to QTc Interval in Rheumatoid Arthritis.Archives of rheumatology · 2026Article
- Hypokalemic Quadriparesis as the Initial Presentation of Primary Sjögren's Syndrome With Distal Renal Tubular Acidosis: A Case Report.Clinical case reports · 2025Article
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- The challenges of managing distal renal tubular acidosis in pregnant patients with primary Sjögren's disease.BMJ case reports · 2025Article
- Distal Renal Tubular Acidosis: A Conundrum of Short Stature, Failure to Thrive, Rickets, and Nephrocalcinosis.Cureus · 2025Article
- Article
- Preclinical modeling of metabolic syndrome to study the pleiotropic effects of novel antidiabetic therapy independent of obesity.Scientific reports · 2024Article
- Primary Distal Renal Tubular Acidosis: Toward an Optimal Correction of Metabolic Acidosis.Clinical journal of the American Society of Nephrology : CJASN · 2024Review
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- Article
- Article
- Distal Renal Tubular Acidosis in Patients with Autoimmune Diseases-An Update on Pathogenesis, Clinical Presentation and Therapeutic Strategies.Biomedicines · 2022Review
- Hypokalaemic quadriparesis with respiratory failure due to latent Sjogren syndrome.BMJ case reports · 2021Article
- Hypokalaemic paralysis as the initial clinical presentation of Sjogren's syndrome induced distal renal tubular acidosis.BMJ case reports · 2021Article
- Renal Tubular Acidosis and Management Strategies: A Narrative Review.Advances in therapy · 2021Review
- Efficacy and safety of an innovative prolonged-release combination drug in patients with distal renal tubular acidosis: an open-label comparative trial versus standard of care treatments.Pediatric nephrology (Berlin, Germany) · 2021Article
- Hyperkalemia in type 4 renal tubular acidosis associated with systemic lupus erythematosus.Rheumatology international · 2020Review
- Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDistal renal tubular acidosis is a relatively infrequent condition with complex pathophysiology that can present with life-threatening electrolyte abnormalities. CASE PRESENTATION: We describe a case of a 57-year-old Caucasian woman with previous episodes of hypokalemia, severe muscle weakness, and fatigue. Upon further questioning, symptoms of dry eye and dry mouth became evident. Initial evaluation revealed hyperchloremic metabolic acidosis, severe hypokalemia, persistent alkaline urine, and a positive urinary anion gap, suggestive of distal renal tubular acidosis. Additional laboratory workup and renal biopsy led to the diagnosis of primary Sjögren's syndrome with associated acute tubulointerstitial nephritis. After potassium and bicarbonate supplementation, immunomodulatory therapy with hydroxychloroquine, azathioprine, and prednisone was started. Nonetheless, her renal function failed to improve and remained steady with an estimated glomerular filtration rate of 42 ml/min/1.73 m
conclusionsCases of renal tubular acidosis should be carefully evaluated to prevent adverse complications, uncover a potentially treatable condition, and prevent the progression to chronic kidney disease. Repeated episodes of unexplained hypokalemia could be an important clue for diagnosis.
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