Evidence map›Paper›PMID 31023312›Full record

ArticleMicrobial cell factories2019

Developing a single strain for in vitro salvage synthesis of NAD

Hironori Taniguchi, Makoto Imura, Kenji Okano, Kohsuke Honda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial cell factories, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hironori TaniguchiDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka, 565-0871, Japan.
Makoto ImuraKOHJIN Life Sciences Co., Ltd., Higashihama 1-6, Saiki, Oita, 876-858, Japan.
Kenji OkanoDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka, 565-0871, Japan.
Kohsuke HondaDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka, 565-0871, Japan. honda@bio.eng.osaka-u.ac.jp.ORCID http://orcid.org/0000-0001-9069-7574
The University of Osaka · JP

Funding

Japan Science and Technology Agency A-STEP (Stage II)Japan Society for the Promotion of Science 17K07720Japan Society for the Promotion of Science 18J00236
6 · The paper itself

Abstract

backgroundThermostable enzymes have several advantages over their mesophilic counterparts for industrial applications. However, trade-offs such as thermal instability of enzyme substrates or co-factors exist. Nicotinamide adenine dinucleotide (NAD

resultsAn integrated strain, E. coli DH5α (pBR-CI857, pGETS118-NAD

conclusionsThe integrated strain allows preparation of an enzyme cocktail that can solve the problem of NAD

Indexed as

Hot TemperatureMetabolic Networks and PathwaysCatalysisEnzyme StabilityEscherichia coliMetabolic EngineeringNADOperonNADArtificial operonCascade reactionIn vitro metabolic engineeringNAD+OGABThermophilic enzyme

Identifiers

PMID31023312
PMCPMC6482498
OpenAlexW2940848241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.