Evidence map›Paper›PMID 31023126›Full record

ArticleJournal of the American Heart Association2019

Comparison of Patient-Reported Care Satisfaction, Quality of Warfarin Therapy, and Outcomes of Atrial Fibrillation: Findings From the ORBIT - AF Registry.

Alexander C Perino, Peter Shrader, Mintu P Turakhia, Jack E Ansell, Bernard J Gersh, Gregg C Fonarow, Alan S Go, Daniel W Kaiser, Elaine M Hylek, Peter R Kowey and 6 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 1 country.

Alexander C Perino1 Stanford Center for Clinical Research Stanford University School of Medicine Stanford CA.
Peter Shrader2 Duke Clinical Research Institute Duke University Durham NC.
Mintu P Turakhia1 Stanford Center for Clinical Research Stanford University School of Medicine Stanford CA.
Jack E Ansell3 Hofstra North Shore/LIJ School of Medicine Hempstead NY.
Bernard J Gersh4 Mayo Clinic College of Medicine Mayo Clinic Rochester MN.
Gregg C Fonarow5 Division of Cardiology Ronald Regan-UCLA Medical Center Los Angeles CA.
Alan S Go6 Kaiser Permanente Northern California Oakland CA.
Daniel W Kaiser1 Stanford Center for Clinical Research Stanford University School of Medicine Stanford CA.
Elaine M Hylek7 Boston University School of Medicine Boston MA.
Peter R Kowey8 Lankenau Institute for Medical Research Wynnewood PA.
Daniel E Singer9 Department of Medicine Massachusetts General Hospital Boston MA.
Laine Thomas2 Duke Clinical Research Institute Duke University Durham NC.
Benjamin A Steinberg10 Division of Cardiovascular Medicine University of Utah Salt Lake City UT.
Eric D Peterson2 Duke Clinical Research Institute Duke University Durham NC.
Jonathan P Piccini2 Duke Clinical Research Institute Duke University Durham NC.
Kenneth W Mahaffey1 Stanford Center for Clinical Research Stanford University School of Medicine Stanford CA.
Clinical Research Institute · USStanford University · USBoston University · USCenter for Clinical Research (United States) · USDuke University · USHofstra University · USKaiser Permanente · USLankenau Institute for Medical Research · USMassachusetts General Hospital · USMayo Clinic in Arizona · USUCLA Medical Center · USUniversity of Utah · US

Funding

T32 Training Program in Mechanisms and Innovation in Vascular DiseaseT32HL098049 · NHLBI · STANFORD UNIVERSITY · PI Nicholas James Leeper, Philip S Tsao · 2010 to 2026
$6.3M
Optimizing Outcomes for Patients with Heart Failure and Atrial FibrillationK23HL143156 · NHLBI · UNIVERSITY OF UTAH · PI STEINBERG, BENJAMIN ADAM · 2018 to 2022
$951k
NHLBI NIH HHS K23 HL143156
6 · The paper itself

Abstract

Background Patient satisfaction with therapy is an important metric of care quality and has been associated with greater medication persistence. We evaluated the association of patient satisfaction with warfarin therapy to other metrics of anticoagulation care quality and clinical outcomes among patients with atrial fibrillation ( AF ). Methods and Results Using data from the ORBIT - AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation) registry, patients were identified with AF who were taking warfarin and had completed an Anti-Clot Treatment Scale ( ACTS ) questionnaire, a validated metric of patient-reported burden and benefit of oral anticoagulation. Multivariate regressions were used to determine association of ACTS burden and benefit scores with time in therapeutic international normalized ratio range ( TTR ; both ≥75% and ≥60%), warfarin discontinuation, and clinical outcomes (death, stroke, major bleed, and all-cause hospitalization). Among 1514 patients with AF on warfarin therapy (75±10 years; 42% women; CHA

Indexed as

Medication AdherenceAgedAged, 80 and overAge FactorsAnti-Arrhythmia AgentsAnticoagulantsAtrial FibrillationFemaleHemorrhageHospitalizationHumansInternational Normalized RatioMaleMiddle AgedMortalityMultivariate AnalysisAnti-Arrhythmia AgentsAnticoagulantsWarfarinanticoagulationatrial fibrillationpatient‐centered carepatient‐reported outcomewarfarin

Identifiers

PMID31023126
PMCPMC6512133
OpenAlexW2941996240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.