Evidence map›Paper›PMID 31022988›Full record

ReviewInternational journal of molecular sciences2019

Acyl-CoA-Binding Domain-Containing 3 (ACBD3; PAP7; GCP60): A Multi-Functional Membrane Domain Organizer.

Xihua Yue, Yi Qian, Bopil Gim, Intaek Lee

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Infection and immunity · 2026
    Article
  2. Review
  3. Review
  4. Subcellular Stress Markers in Epithelial Ovarian Cancer.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. TheJournal of bacteriology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. ACBD3 Bioinformatic Analysis and Protein Expression in Breast Cancer Cells.International journal of molecular sciences · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xihua YueSchool of Life Science and Technology, ShanghaiTech University, Pudong, Shanghai 201210, China. yuexh@shanghaitech.edu.cn.
Yi QianSchool of Life Science and Technology, ShanghaiTech University, Pudong, Shanghai 201210, China. qianyi@shanghaitech.edu.cn.
Bopil GimSchool of Physical Science and Technology, ShanghaiTech University, Pudong, Shanghai 201210, China. bgim@shanghaitech.edu.cn.ORCID 0000-0001-5880-0789
Intaek LeeSchool of Life Science and Technology, ShanghaiTech University, Pudong, Shanghai 201210, China. Leeintaek@shanghaitech.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acyl-CoA-binding domain-containing 3 (ACBD3) is a multi-functional scaffolding protein, which has been associated with a diverse array of cellular functions, including steroidogenesis, embryogenesis, neurogenesis, Huntington's disease (HD), membrane trafficking, and viral/bacterial proliferation in infected host cells. In this review, we aim to give a timely overview of recent findings on this protein, including its emerging role in membrane domain organization at the Golgi and the mitochondria. We hope that this review provides readers with useful insights on how ACBD3 may contribute to membrane domain organization along the secretory pathway and on the cytoplasmic surface of intracellular organelles, which influence many important physiological and pathophysiological processes in mammalian cells.

Indexed as

Adaptor Proteins, Signal TransducingAnimalsBiological TransportCeramidesGlucosylceramidesGolgi ApparatusHumansHuntington DiseaseIronLipid MetabolismMembrane ProteinsMitochondriaModels, MolecularNeoplasmsSteroidsACBD3 protein, humanAdaptor Proteins, Signal TransducingCeramidesGlucosylceramidesIronMembrane ProteinsSteroidsACBD3GCP60GolgiPAP7PI4KB

Identifiers

PMID31022988
PMCPMC6514682

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.