Evidence map›Paper›PMID 31022947›Full record

ArticleInternational journal of molecular sciences2019

Improvement of l-Leucine Production in

Ying-Yu Wang, Feng Zhang, Jian-Zhong Xu, Wei-Guo Zhang, Xiu-Lai Chen, Li-Ming Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. EngineeringBiodesign research · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Engineered3 Biotech · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ying-Yu WangThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800# Lihu Road, Wuxi 214122, China. wangyy0711@163.com.
Feng ZhangThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800# Lihu Road, Wuxi 214122, China. zhang20180606@sina.com.
Jian-Zhong XuThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800# Lihu Road, Wuxi 214122, China. xujianzhong@jiangnan.edu.cn.ORCID 0000-0003-0750-6875
Wei-Guo ZhangThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800# Lihu Road, Wuxi 214122, China. zhangwg168@163.com.
Xiu-Lai ChenState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China. shirleyl1205@163.com.
Li-Ming LiuState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China. peidongchen13@163.com.
Jiangnan University · CN

Funding

China Postdoctoral Science Foundation Grant 2016M590410National First-class Discipline Program of Light Industry Technology and Engineering LITE2018-07the National Natural Science Foundation of China 31601459
6 · The paper itself

Abstract

The production of l-leucine was improved by the disruption of

Indexed as

Biosynthetic PathwaysBacterial ProteinsCorynebacterium glutamicumGlutamate Dehydrogenase (NADP+)Ketol-Acid ReductoisomeraseLeucineLeucine DehydrogenaseMetabolic EngineeringOxidation-ReductionBacterial ProteinsGlutamate Dehydrogenase (NADP+)Ketol-Acid ReductoisomeraseLeucineLeucine Dehydrogenaseacetohydroxyacid isomeroreductaseCorynebacterium glutamicumleucine dehydrogenasel-leucineNAD-dependent glutamate dehydrogenase

Identifiers

PMID31022947
PMCPMC6515235
OpenAlexW2942243704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.