ArticleToxins2019
Uremic Toxin Concentrations are Related to Residual Kidney Function in the Pediatric Hemodialysis Population.
Open access · goldAbstract read
In one paragraph
Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Pooled it
- Impact of Uremic Toxins on Endothelial Dysfunction in Chronic Kidney Disease: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Protein-bound uremic toxin lowering strategies in chronic kidney disease: a systematic review and meta-analysis.Journal of nephrology · 2021Pooled it
- Trial
- Adequacy of dialysis in children and adolescents: more than just Kt/V.Pediatric nephrology (Berlin, Germany) · 2026Review
- The gut-kidney axis in pediatric acute kidney injury: a review of pathophysiological mechanisms and therapeutic frontiers.Pediatric nephrology (Berlin, Germany) · 2026Review
- Correlation of serum beta-2 microglobulin with hemodialysis prescription and comorbid factors in children undergoing chronic hemodialysis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Tryptophan metabolites clearance in hemodialyzed patients.Amino acids · 2026Article
- Review
- Monitoring of Allograft Adaptation After Kidney Transplantation in Pediatric Patients by Targeted Plasma Metabolomics.International journal of molecular sciences · 2025Article
- Gut-derived metabolites as treatment targets in chronic kidney disease-an avenue toward personalized medicine.Pediatric nephrology (Berlin, Germany) · 2025Article
- Pre-transplant residual diuresis and oxalic acid concentration influence kidney graft survival.PloS one · 2025Article
- Role of Uremic Toxins in Vascular Inflammation Associated with Chronic Kidney Disease.Journal of clinical medicine · 2024Article
- Effects of fecal microbiota transplantation for recurrent Clostridium difficile infection in children on kidney replacement therapy: a pilot study.Pediatric nephrology (Berlin, Germany) · 2024Article
- Delayed Graft Function After Kidney Transplantation: The Role of Residual Diuresis and Waste Products, as Oxalic Acid and Its Precursors.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Immunosenescence and Immune Exhaustion Are Associated with Levels of Protein-Bound Uremic Toxins in Patients on Hemodialysis.Biomedicines · 2023Article
- The benefits of dietary fiber: the gastrointestinal tract and beyond.Pediatric nephrology (Berlin, Germany) · 2023Review
- Hidden risks associated with conventional short intermittent hemodialysis: A call for action to mitigate cardiovascular risk and morbidity.World journal of nephrology · 2022Review
- Classification of Uremic Toxins and Their Role in Kidney Failure.Clinical journal of the American Society of Nephrology : CJASN · 2021Review
- Gut Microbiome Profiling Uncovers a Lower Abundance ofJournal of personalized medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 17 institutions in 10 countries.
Evelien SnauwaertGhent University Hospital, 9000 Ghent, Belgium. evelien.snauwaert@uzgent.be.ORCID 0000-0003-2660-7460
Els HolvoetGhent University Hospital, 9000 Ghent, Belgium. els.holvoet@uzgent.be.
Wim Van BiesenGhent University Hospital, 9000 Ghent, Belgium. wim.vanbiesen@ugent.be.ORCID 0000-0002-4782-5224
Ann RaesGhent University Hospital, 9000 Ghent, Belgium. ann.raes@ugent.be.ORCID 0000-0001-7809-2505
Griet GlorieuxGhent University Hospital, 9000 Ghent, Belgium. griet.glorieux@ugent.be.ORCID 0000-0002-7641-4707
Johan Vande WalleGhent University Hospital, 9000 Ghent, Belgium. johan.vandewalle@uzgent.be.
Sanne RoelsDepartment of Data Analysis, Faculty of Psychology and Pedagogy, Ghent University, 9000 Ghent, Belgium. sanne.roels@ugent.be.
Raymond VanholderGhent University Hospital, 9000 Ghent, Belgium. Raymond.vanholder@ugent.be.
Varvara AskitiA & P Kyriakou Children's Hospital, 11527 Athens, Greece. vaskiti@gmail.com.
Karolis AzukaitisClinic of Pediatrics, Faculty of Medicine, Vilnius University, 08406 Vilnius, Lithuania. k.azukaitis@gmail.com.
Aysun BayazitDepartment of Pediatric Nephrology, Cukurova University, 01330 Adana, Turkey. ayskar@cu.edu.tr.
Nur CanpolatDepartment of Pediatric Nephrology, Istanbul University Cerrahpasa School of Medicine, 34096 Istanbul, Turkey. ncanpolat2000@hotmail.com.ORCID 0000-0002-3420-9756
Michel FischbachChildren's Dialysis Center, 67098 Strasbourg, France. fischbam@gmail.com.
Nathalie GodefroidDepartment of Pediatric Nephrology, Université Catholique Louvain, 1200 Brussels, Belgium. nathalie.godefroid@uclouvain.be.ORCID 0000-0002-7354-4741
Saoussen KridHôpital Necker-Enfants Malades, 75015 Paris, France. saoussen.krid@aphp.fr.
Mieczyslaw LitwinDepartment of Nephrology, Kidney Transplantation and Hypertension, Children's Memorial Health Institute, 04-730 Warsaw, Poland. M.Litwin@IPCZD.PL.
Lukasz ObryckiDepartment of Nephrology, Kidney Transplantation and Hypertension, Children's Memorial Health Institute, 04-730 Warsaw, Poland. obrycki.lukasz@gmail.com.ORCID 0000-0002-5134-8643
Fabio PaglialongaPediatric Nephrology Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy. fabio.paglialonga@policlinico.mi.it.
Bruno RanchinHôpital Femme Mère Enfant, Hospices Civils de Lyon, 69677 Bron, France. bruno.ranchin@chu-lyon.fr.
Charlotte SamailleCHU Lille, Service de Néphrologie Pédiatrique, 59000 Lille, France. charlotte.samaille@chru-lille.fr.
Franz SchaeferCenter for Pediatrics and Adolescent Medicine, 69120 Heidelberg, Germany. franz.schaefer@med.uni-heidelberg.de.ORCID 0000-0001-7564-9937
Claus Peter SchmittCenter for Pediatrics and Adolescent Medicine, 69120 Heidelberg, Germany. clauspeter.schmitt@med.uni-heidelberg.de.ORCID 0000-0002-9688-9515
Brankica SpasojevicUniversity Children's Hospital, Belgrade and School of Medicine, University of Belgrade, 11000 Belgrade, Serbia. brankicaspasojevic@yahoo.com.
Constantinos J StefanidisA & P Kyriakou Children's Hospital, 11527 Athens, Greece. cjstefanidis@gmail.com.
Maria Van DyckDepartment of Pediatric Nephrology, Leuven University Hospital, 3000 Leuven, Belgium. maria.vandyck@uzleuven.be.
Koen Van HoeckDepartment of Pediatric Nephrology, Antwerp University, 2650 Antwerp, Belgium. koen.vanhoeck@uza.be.
Laure CollardDepartment of Pediatric Nephrology, CHU Liège, 4000 Liège, Belgium. laure.collard@chc.be.
Sunny ElootGhent University Hospital, 9000 Ghent, Belgium. sunny.eloot@ugent.be.ORCID 0000-0002-6984-1743
Rukshana ShroffGreat Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK. rukshana.shroff@gosh.nhs.uk.
Ghent University Hospital · BEChildren's Memorial Health Institute · PLHeidelberg University · DEPanagiotis & Aglaia Kyriakou Children's Hospital · GRCentre Hospitalier Universitaire de Lille · FRCukurova University · TRFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITGhent University · BEGreat Ormond Street Hospital for Children NHS Foundation Trust · GBHôpital Femme Mère Enfant · FRHôpital Necker-Enfants Malades · FRIstanbul University-Cerrahpaşa · TRKU Leuven · BEUCLouvain · BEUniversity of Belgrade · RSUniversity of Liège · BEVilnius University · LT
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein-bound uremic toxins (PBUTs) play a role in the multisystem disease that children on hemodialysis (HD) are facing, but little is known about their levels and protein binding (%PB). In this study, we evaluated the levels and %PB of six PBUTs cross-sectionally in a large pediatric HD cohort (
Indexed as
Renal DialysisUremiaAdolescentChildChild, PreschoolFemaleHumansKidneyMaleProtein BindingRenal Insufficiency, ChronicToxins, BiologicalToxins, Biologicalchildchronic kidney diseaseend-stage kidney diseasehemodialysisresidual kidney functionuremic toxins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.