Evidence map›Paper›PMID 31022845›Full record

ArticleMedicines (Basel, Switzerland)2019

Camptothecin Induces PD-L1 and Immunomodulatory Cytokines in Colon Cancer Cells.

Deepa Bedi, Henry J Henderson, Upender Manne, Temesgen Samuel

Open access · goldAbstract read
In one paragraph

Article in Medicines (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Deepa BediCollege of Veterinary Medicine. Tuskegee University, Tuskegee, AL 36088, USA. dbedi@tuskegee.edu.
Henry J HendersonCollege of Veterinary Medicine. Tuskegee University, Tuskegee, AL 36088, USA. hhenderson0533@tuskegee.edu.
Upender ManneDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. upendermanne@uabmc.edu.
Temesgen SamuelCollege of Veterinary Medicine. Tuskegee University, Tuskegee, AL 36088, USA. tsamuel@tuskegee.edu.
Tuskegee University · USUniversity of Alabama at Birmingham · US

Funding

Evaluation of HSPD1 (Heat Shock Protein, 60) as a theranostic target for breast cancerSC1GM136521 · NIGMS · TUSKEGEE UNIVERSITY · PI BEDI, DEEPA · 2020 to 2023
$1.5M
Phage Display to Identify Epithelial to Mesenchymal Transitioned (EMT) Breast Cancer CellsSC2CA211028 · NCI · TUSKEGEE UNIVERSITY · PI BEDI, DEEPA · 2016 to 2018
$441k
NCI NIH HHS SC2 CA211028NIGMS NIH HHS SC1 GM136521NIH HHS GM109314, CA211028, CA118948, MD007585
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

camptothecincolon cancercytokineimmunotherapyPD-L1topoisomerase inhibition

Identifiers

PMID31022845
PMCPMC6631458
OpenAlexW2940960484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.