Evidence map›Paper›PMID 31022493›Full record

ArticleToxicology and applied pharmacology2019

Toxicokinetics and bioavailability of bisphenol AF following oral administration in rodents: A dose, species, and sex comparison.

Suramya Waidyanatha, Sherry R Black, Kristin Aillon, Brad Collins, Purvi R Patel, Felicia Riordan, Vicki Sutherland, Veronica Godfrey Robinson, Reshan Fernando, Timothy R Fennell

Open access · greenAbstract readComparative Study
In one paragraph

Article in Toxicology and applied pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Suramya WaidyanathaDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States of America. Electronic address: waidyanathas@niehs.nih.gov.
Sherry R BlackRTI International, Discovery Sciences, Research Triangle Park, NC, United States of America.
Kristin AillonMRIGlobal, Kansas City, MO, United States of America.
Brad CollinsDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States of America.
Purvi R PatelRTI International, Discovery Sciences, Research Triangle Park, NC, United States of America.
Felicia RiordanMRIGlobal, Kansas City, MO, United States of America.
Vicki SutherlandDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States of America.
Veronica Godfrey RobinsonDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States of America.
Reshan FernandoRTI International, Discovery Sciences, Research Triangle Park, NC, United States of America.
Timothy R FennellRTI International, Discovery Sciences, Research Triangle Park, NC, United States of America.
National Institute of Environmental Health Sciences · USRTI International · USMRIGlobal · US

Funding

Toxicological Assessments for the National Toxicology ProgramZIAES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2016 to 2019
$31.9M
NIEHS NIH HHS HHSN273201400004CNIEHS NIH HHS HHSN273201400020CNIEHS NIH HHS HHSN273201400022C
6 · The paper itself

Abstract

We investigated the toxicokinetics and bioavailability of bisphenol AF (BPAF) in male and female Harlan Sprague Dawley rats and B6C3F1/N mice following a single gavage administration of 34, 110, or 340 mg/kg. A validated analytical method was used to quantitate free (unconjugated parent) and total (unconjugated and conjugated) BPAF in plasma. BPAF was rapidly absorbed in rats with the maximum plasma concentration, C

Indexed as

Administration, OralAnimalsBenzhydryl CompoundsBiological AvailabilityBisphenol A CompoundsEndocrine DisruptorsFemaleGastrointestinal AbsorptionHalf-LifeMaleMetabolic Clearance RateMicePhenolsRats, Sprague-DawleyRisk AssessmentSex FactorsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsPhenolsBioavailabilityBisphenol AFToxicokinetics

Identifiers

PMID31022493
PMCPMC7178755
OpenAlexW2943443938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.