Evidence map›Paper›PMID 31022306›Full record

ArticleClinical transplantation2019

Arenaviruses and West Nile Virus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.

Judith A Anesi, Fernanda P Silveira, AST Infectious Diseases Community of Practice

Open access · greenAbstract read
In one paragraph

Article in Clinical transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Neuroinvasive West Nile virus infections after solid organ transplantation: Single center experience and systematic review.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Emergency Department Presentations of West Nile Virus.The western journal of emergency medicine · 2025
    Article
  6. Article
  7. A Scoping Review of Arthropod-Borne Flavivirus Infections in Solid Organ Transplant Recipients.Transplant infectious disease : an official journal of the Transplantation Society · 2024
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Coronavirus disease 2019: Implications of emerging infections for transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
  14. Emerging and neglected zoonoses in transplant population.World journal of transplantation · 2020
    Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Judith A AnesiDivision of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Fernanda P SilveiraDivision of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania.
AST Infectious Diseases Community of Practice
University of Pennsylvania · USUniversity of Pittsburgh Medical Center · US

Funding

Impact of donor bacterial infections on solid organ transplant recipient outcomesK01AI137317 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ANESI, JUDITH · 2019 to 2023
$722k
NIAID NIH HHS K01 AI137317
6 · The paper itself

Abstract

These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation review the epidemiology, diagnosis, prevention, and management of infection due to Arenaviruses and West Nile Virus (WNV) in the pre- and post-transplant period. Arenaviruses and WNV have been identified as causes of both donor-derived and post-transplant infection. Most data related to these infections have been published in case reports and case series. Transplant recipients may become infected with Arenaviruses if they, or their donors, are exposed to wild rodents or infected pet rodents. Lymphocytic choriomeningitis virus is the most commonly recognized Arenavirus among transplant recipients and should be considered when transplant recipients present with fever, hepatitis, meningitis/encephalitis, and/or multisystem organ failure. WNV is a mosquito-borne virus, and as such, its incidence varies yearly depending on environmental conditions. WNV in transplant recipients typically presents with fever, myalgias, and rash; approximately one in 40 develop neuroinvasive disease. Due to its morbidity, the Organ Procurement and Transplantation Network recently mandated that transplant centers screen living donors for WNV infection in endemic areas. Little is known about the optimal treatment of Arenaviruses or WNV; reduction in immunosuppression and supportive care are the mainstays of management at present.

Indexed as

Antiviral AgentsHumansOrgan TransplantationPractice Guidelines as TopicSocieties, MedicalTransplant RecipientsWest Nile FeverWest Nile virusAntiviral Agentsdonor-derived infectionsdonors and donationinfection and infectious agentsinfectiousviralWest Nile

Identifiers

PMID31022306
PMCPMC6786906
OpenAlexW2940599363

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.