ArticlePloS one2019
RNA-sequencing analysis reveals betalains metabolism in the leaf of Amaranthus tricolor L.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- Searching for Amaranthin-A Multipotential Betacyanin from Natural Sources and In Vitro Cultures.International journal of molecular sciences · 2026Review
- Response surface optimization of abiotic elicitors for betalain production and antioxidant capacity in Celosia argentea cell suspension cultures.Scientific reports · 2025Article
- Identification of R2R3-MYB Transcription Factor Family Based onPlants (Basel, Switzerland) · 2025Article
- Amaranth Plants with Various Color Phenotypes Recruit Different Soil Microorganisms in the Rhizosphere.Plants (Basel, Switzerland) · 2024Article
- Genome-Wide Identification of the Cation/Proton Antiporter (CPA) Gene Family and Functional Analysis of AtrNHX8 under Salt Stress.Plants (Basel, Switzerland) · 2024Article
- Amaranth's Growth and Physiological Responses to Salt Stress and the Functional Analysis ofInternational journal of molecular sciences · 2024Article
- Comparative Transcriptomic Analysis of the Metabolism of Betalains and Flavonoids in Red Amaranth Hypocotyl under Blue Light and Dark Conditions.Molecules (Basel, Switzerland) · 2023Article
- Identification of WRKY gene family members in amaranth based on a transcriptome database and functional analysis ofFrontiers in plant science · 2023Article
- Amaranth as a natural food colorant source: Survey of germplasm and optimization of extraction methods for betalain pigments.Frontiers in plant science · 2022Article
- A short-term cooling of root-zone temperature increases bioactive compounds in baby leafFrontiers in plant science · 2022Article
- Article
- Elucidation of the core betalain biosynthesis pathway in Amaranthus tricolor.Scientific reports · 2021Article
- Research Progress of Betalain in Response to Adverse Stresses and Evolutionary Relationship Compared with Anthocyanin.Molecules (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amaranth plants contain large amounts of betalains, including betaxanthins and betacyanins. Amaranthin is a betacyanin, and its molecular structure and associated metabolic pathway differ from those of betanin in beet plants. The chlorophyll, carotenoid, betalain, and flavonoid contents in amaranth leaves were analyzed. The abundance of betalain, betacyanin, and betaxanthin was 2-5-fold higher in the red leaf sectors than in the green leaf sectors. Moreover, a transcriptome database was constructed for the red and green sectors of amaranth leaves harvested from 30-day-old seedlings. 22 unigenes were selected to analyze the expression profiles in the two leaf sectors. The RNA-sequencing data indicated that many unigenes are involved in betalain metabolic pathways. The potential relationships between diverse metabolic pathways and betalain metabolism were analyzed. The validation of the expression of 22 selected unigenes in a qRT-PCR assay revealed the genes that were differentially expressed in the two leaf sectors. Betalains were biosynthesized in specific tissues of the red sectors of amaranth leaves. Almost all of the genes related to betalain metabolism were identified in the transcriptome database, and the expression profiles were different between the red sectors and green sectors in the leaf. Amaranth plants consist of diverse metabolic pathways, and the betalain metabolic pathway is linked to a group of other metabolic pathways.
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