ArticlePLoS neglected tropical diseases2019
Clinical and molecular epidemiology of Crimean-Congo hemorrhagic fever in Oman.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Crimean-Congo hemorrhagic fever in the Arab world: A systematic review.Frontiers in veterinary science · 2022Pooled it
- Crimean-congo hemorrhagic fever in Iraq, 2021-2024: epidemiological and clinical data analysis with proposed severity indicators for resource-constrained settings.BMC infectious diseases · 2026Article
- TheSultan Qaboos University medical journal · 2026Article
- Detecting spatial clusters of Crimean Congo hemorrhagic fever in Iraq in 2023.Global epidemiology · 2025Article
- Serosurveillance of Crimean-Congo hemorrhagic fever virus antibodies in livestock as a reservoir for human infection in Afghanistan.One health (Amsterdam, Netherlands) · 2025Article
- Article
- Crimean-Congo hemorrhagic fever, a real health problem in Iraq?IJID regions · 2025Article
- A comprehensive review on the epidemiology of arboviruses in the Eastern Mediterranean Region (EMRO): insights from the WHO's Regional Office.GMS hygiene and infection control · 2025Article
- Crimean-Congo Hemorrhagic Fever Virus Infections in Slaughtered Camels and Abattoir Workers in the United Arab Emirates.Transboundary and emerging diseases · 2025Article
- Control strategies for emerging infectious diseases: Crimean-Congo hemorrhagic fever management.Health science reports · 2024Article
- Recent Advances in Crimean-Congo Hemorrhagic Fever Virus Detection, Treatment, and Vaccination: Overview of Current Status and Challenges.Biological procedures online · 2024Review
- A retrospective study of Crimean-Congo hemorrhagic fever in Iraq.African health sciences · 2024Article
- Crimean-Congo hemorrhagic fever, transfer patterns, vectors and history in Iran and neighboring countries.Veterinary research forum : an international quarterly journal · 2024Review
- Crimean-Congo hemorrhagic fever virus in Central, Eastern, and South-eastern Asia.Virologica Sinica · 2023Review
- Distribution pattern of Crimean-Congo Hemorrhagic Fever in Asia and the Middle East.Frontiers in public health · 2023Review
- Clinical and Epidemiological Characteristics of 30 Fatal Cases of Crimean-Congo Hemorrhagic Fever in Kabul, Afghanistan: A Retrospective Observational Study.Infection and drug resistance · 2023Article
- Emerging and Re-emerging Infectious Diseases in the WHO Eastern Mediterranean Region, 2001-2018.International journal of health policy and management · 2022Review
- History and classification of Aigai virus (formerly Crimean-Congo haemorrhagic fever virus genotype VI).The Journal of general virology · 2022Article
- Clinical and Molecular Epidemiology of Crimean-Congo Hemorrhagic Fever in Humans in Uganda, 2013-2019.The American journal of tropical medicine and hygiene · 2021Article
- Crimean-Congo Hemorrhagic Fever Virus in Asia, Africa and Europe.Microorganisms · 2021Review
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12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCrimean-Congo hemorrhagic fever (CCHF) is a serious disease with a high fatality rate reported in many countries. The first case of CCHF in Oman was detected in 1995 and serosurveys have suggested widespread infection of humans and livestock throughout the country. METHODOLOGY: Cases of CCHF reported to the Ministry of Health (MoH) of Oman between 1995 and 2017 were retrospectively reviewed. Diagnosis was confirmed by serology and/or molecular tests in Oman. Stored RNA from recent cases was studied by sequencing the complete open reading frame (ORF) of the viral S segment at Public Health England, enabling phylogenetic comparisons to be made with other S segments of strains obtained from the region.
findingsOf 88 cases of CCHF, 4 were sporadic in 1995 and 1996, then none were detected until 2011. From 2011-2017, incidence has steadily increased and 19 (23.8%) of 80 cases clustered around Eid Al Adha. The median (range) age was 33 (15-68) years and 79 (90%) were male. The major risk for infection was contact with animals and/or butchering in 73/88 (83%) and only one case was related to tick bites alone. Severe cases were over-represented: 64 (72.7%) had a platelet count < 50 x 109/L and 32 (36.4%) died. There was no intrafamilial spread or healthcare-associated infection. The viral S segments from 11 patients presenting in 2013 and 2014 were all grouped in Asia 1 (IV) lineage.
conclusionsCCHF is well-established throughout Oman, with a single strain of virus present for at least 20 years. Most patients are men involved in animal husbandry and butchery. The high mortality suggests that there is substantial under-diagnosis of milder cases. Preventive measures have been introduced to reduce risks of transmission to animal handlers and butchers and to maintain safety in healthcare settings.
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