Evidence map›Paper›PMID 31021986›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2019

Sharing of Injection Drug Preparation Equipment Is Associated With HIV Infection: A Cross-sectional Study.

Laura J Ball, Klajdi Puka, Mark Speechley, Ryan Wong, Brian Hallam, Joshua C Wiener, Sharon Koivu, Michael S Silverman

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV - CDC Recommendations, United States, 2025.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2025
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  20. The hepatitis C epidemic in Canada: An overview of recent trends in surveillance, injection drug use, harm reduction and treatment.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura J BallDepartment of Medicine, St. Joseph's Health Care London, Western University, London, Ontario, Canada.
Klajdi PukaDepartment of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
Mark SpeechleyDepartment of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
Ryan WongDepartment of Medicine, St. Joseph's Health Care London, Western University, London, Ontario, Canada.
Brian HallamDepartment of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
Joshua C WienerDepartment of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
Sharon KoivuDepartment of Family Medicine, The Western Centre for Public Health and Family Medicine, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.
Michael S SilvermanDepartment of Medicine, St. Joseph's Health Care London, Western University, London, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSharing needles/syringes and sexual transmission are widely appreciated as means of HIV transmission among persons who inject drugs (PWIDs). London, Canada, is experiencing an outbreak of HIV among PWIDs, despite a large needle/syringe distribution program and low rates of needle/syringe sharing.

objectiveTo determine whether sharing of injection drug preparation equipment (IDPE) is associated with HIV infection.

methodsBetween August 2016 and June 2017, individuals with a history of injection drug use and residence in London were recruited to complete a comprehensive questionnaire and HIV testing.

resultsA total of 127 participants were recruited; 8 were excluded because of failure to complete HIV testing. The remaining 35 HIV-infected (cases) and 84 HIV-uninfected (controls) participants were assessed. Regression analysis found that sharing IDPE, without sharing needles/syringes, was strongly associated with HIV infection (adjusted odds ratio: 22.1, 95% confidence interval: 4.51 to 108.6, P < 0.001).

conclusionsSharing of IDPE is a risk factor for HIV infection among PWIDs, even in the absence of needle/syringe sharing. Harm reduction interventions to reduce HIV transmission associated with this practice are urgently needed.

Indexed as

Drug CompoundingInjectionsAdultCanadaCross-Sectional StudiesDisease OutbreaksFemaleHIV InfectionsHumansLondonMaleMiddle AgedNeedle SharingPublic HealthRisk FactorsRisk-Taking

Identifiers

PMID31021986
PMCPMC6905403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.