ArticlePlant signaling & behavior2019
miR393s regulate salt stress response pathway in Arabidopsis thaliana through scaffold protein RACK1A mediated ABA signaling pathways.
Article in Plant signaling & behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- The PtoERF1-PtomiR393a-PtoFBL4 module confers drought tolerance via ABA-auxin crosstalk in Populus.The New phytologist · 2026Article
- Harnessing microRNA regulatory networks for engineering climate resilience and nutritional enhancement in millets.Stress biology · 2026Review
- Stu-miR393-5p-StTIR1A-StPLC2 module regulates the development of adventitious and lateral roots of potato.Plant cell reports · 2026Article
- RACK1A interacts and colocalizes with FSD1 in stress granules to regulate salt stress response in Arabidopsis.Plant physiology · 2026Article
- Molecular basis of salinity stress tolerance in wheat: implications for crop resilience.Plant molecular biology · 2025Review
- AtGADD45A forms a complex with the scaffold protein AtRACK1A in response to DNA damage.Plant cell reports · 2025Article
- The Role of MicroRNA-Based Strategies in Optimizing Plant Biomass Composition for Bio-Based Packaging Materials.Plants (Basel, Switzerland) · 2025Review
- The TaNHLP1-TaRACK1A module regulates tillering via abscisic acid signaling in wheat.Nature communications · 2025Article
- RACK1A positively regulates opening of the apical hook inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Elucidating the molecular basis of salt tolerance in potatoes through miRNA expression and phenotypic analysis.Scientific reports · 2025Article
- New insights into the salt-responsive regulation in eelgrass at transcriptional and post-transcriptional levels.Frontiers in plant science · 2025Article
- MicroRNA analysis reveals 2 modules that antagonistically regulate xylem tracheary element development in Arabidopsis.The Plant cell · 2024Article
- Unveiling synergistic QTLs associated with slow wilting in soybean (Glycine max [L.] Merr.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Comparative analysis of the carrot miRNAome in response to salt stress.Scientific reports · 2023Article
- Integration of mRNA and miRNA Analysis Reveals the Post-Transcriptional Regulation of Salt Stress Response inInternational journal of molecular sciences · 2023Article
- Coordinating Diverse Functions of miRNA and lncRNA in Fleshy Fruit.Plants (Basel, Switzerland) · 2023Review
- Regulatory Small RNAs for a Sustained Eco-Agriculture.International journal of molecular sciences · 2023Review
- Review
- The miR393-Target Module Regulates Plant Development and Responses to Biotic and Abiotic Stresses.International journal of molecular sciences · 2022Review
- The Characters of Non-Coding RNAs and Their Biological Roles in Plant Development and Abiotic Stress Response.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scaffold protein Receptor for Activated C Kinase 1 (RACK1) is a negative regulator of plant stress hormone - abscisic acid (ABA) mediated pathways. RACK1 has been reported to regulate global miRNA biogenesis pathway in C. elegans, humans, and in Arabidopsis. RACK1 regulates different steps of miRNA biogenesis and stability in response to different stimuli in plants. miR393s is implicated in salt stress response pathway through an antagonistic response between the stress hormone ABA-mediated salt stress and growth hormone auxin. Specifically, the known auxin receptor clade transcripts TIR1/AFB2 are the target for the miR393s. By down-regulating the auxin signaling pathways, the miR393s inhibit the regulation of salt tolerance by auxin. Here we show that genetic loss of RACK1A- the predominant member of the three genes family of RACK1 in Arabidopsis, results in the inhibition of miR393 level causing the same salt sensitivities as the individual mir393a or mir393b or the double mutant mir393ab phenotypes. We propose that down-regulation of auxin signaling through RACK1A induced miR393 biogenesis potentially regulates the Arabidopsis acclimation to salinity. Our findings fill up a molecular gap in our understanding of the role of miR393 mediated ABA and auxin-regulated salt stress responses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.