Evidence map›Paper›PMID 31021652›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Pericyte transplantation improves skeletal muscle recovery following hindlimb immobilization.

Michael Munroe, Svyatoslav Dvoretskiy, Amber Lopez, Jiayu Leong, Michael C Dyle, Hyunjoon Kong, Christopher M Adams, Marni D Boppart

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Exercise Training Stimulates the Release of Glutathione Peroxidase 1 (GPX1)-Enriched Extracellular Vesicles That Promote Angiogenesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Article
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  7. MuSCs and IPCs: roles in skeletal muscle homeostasis, aging and injury.Cellular and molecular life sciences : CMLS · 2024
    Review
  8. Article
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  11. Review
  12. Article
  13. Article
  14. CORP: Gene delivery into murine skeletal muscle using in vivo electroporation.Journal of applied physiology (Bethesda, Md. : 1985) · 2022
    Review
  15. Optimization of a pericyte therapy to improve muscle recovery after limb immobilization.Journal of applied physiology (Bethesda, Md. : 1985) · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Metabolic Coordination of Pericyte Phenotypes: Therapeutic Implications.Frontiers in cell and developmental biology · 2020
    Review
  20. The impact of skeletal muscle contraction on CD146American journal of physiology. Cell physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Michael MunroeDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Svyatoslav DvoretskiyDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Amber LopezDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Jiayu LeongDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Michael C DyleDepartments of Internal Medicine and University of Iowa, Iowa City, Iowa, USA.
Hyunjoon KongDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Christopher M AdamsDepartments of Internal Medicine and University of Iowa, Iowa City, Iowa, USA.
Marni D BoppartDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Urbana University · USUniversity of Iowa · USUniversity of Illinois Urbana-Champaign · US

Funding

Novel Signaling Pathways Underlying Skeletal Muscle AtrophyR01AG060637 · NIA · UNIVERSITY OF IOWA · PI ADAMS, CHRISTOPHER M · 2018 to 2022
$2.6M
Molecular pathogenesis of skeletal muscle atrophyR01AR071762 · NIAMS · UNIVERSITY OF IOWA · PI ADAMS, CHRISTOPHER M · 2017 to 2021
$2.4M
Tissue microenvironment (TIMe) training programT32EB019944 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT, GASKINS, REX · 2016 to 2025
$1.9M
Development of a Cell-Based Therapy to Improve Recovery Following ImmobilizationR01AR072735 · NIAMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, MARNI D. · 2018 to 2022
$1.7M
Development of a Liposomal Nanostimulator to Improve Stem Cell-Based Revascularization TherapiesR21HL131469 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2016 to 2017
$428k
Origins of exercise-brain interactionsR21NS104293 · NINDS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, MARNI D., RHODES, JUSTIN S · 2018 to 2019
$403k
NHLBI NIH HHS R21 HL131469NIAMS NIH HHS R01 AR071762NIAMS NIH HHS R01 AR072735NIA NIH HHS R01 AG060637NIBIB NIH HHS T32 EB019944NINDS NIH HHS R21 NS104293
6 · The paper itself

Abstract

Conditions of extended bed rest and limb immobilization can initiate rapid and significant loss of skeletal muscle mass and function. Physical rehabilitation is standard practice following a period of disuse, yet mobility may be severely compromised, and recovery is commonly delayed or incomplete in special populations. Thus, a novel approach toward recovery of muscle mass is highly desired. Pericytes [neuron-glial antigen 2 (NG2)

Indexed as

Cell TransplantationHindlimb SuspensionAnimalsCapillariesGene Expression ProfilingMaleMiceMice, Inbred C57BLMuscle, SkeletalMuscular AtrophyPericytescapillarydisuse atrophymuscle growthrehabilitationstem cells

Identifiers

PMID31021652
PMCPMC6529341
OpenAlexW2942306090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.