ArticleEpilepsia2019
Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus.
Article in Epilepsia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Identifying common health indicators from paediatric core outcome sets: a systematic review with narrative synthesis using the WHO International Classification of Functioning, Health and Disability.BMJ paediatrics open · 2022Pooled it
- Synthesizing Core Outcome Sets for outcomes research in cohort studies: a systematic review.Pediatric research · 2022Pooled it
- Patient participation in Delphi surveys to develop core outcome sets: systematic review.BMJ open · 2021Pooled it
- Epilepsy-specific patient-reported outcome measures of children's health-related quality of life: A systematic review of measurement properties.Epilepsia · 2020Pooled it
- Randomised controlled trial of online behavioural sleep intervention for children with epilepsy.Scientific reports · 2026Trial
- Trial
- What matters most to people living with epilepsy? A rapid review of qualitative research relating to health outcomes.Epilepsia · 2025Review
- Article
- Article
- Impact of and research priorities in early onset epilepsy: An investigation of parental concerns.Epilepsy & behavior : E&B · 2024Article
- Core outcomes for speech-language services in Ontario schools: a group concept mapping study and guiding framework.BMC health services research · 2024Article
- 'No one's ever said anything about sleep': A qualitative investigation into mothers' experiences of sleep in children with epilepsy.Health expectations : an international journal of public participation in health care and health policy · 2023Article
- Article
- Development of a core outcome set for quality of life for adults with drug-resistant epilepsy: A multistakeholder Delphi consensus study.Epilepsia · 2023Article
- Article
- The Charlotte Project: Recommendations for patient-reported outcomes and clinical parameters in Dravet syndrome through a qualitative and Delphi consensus study.Frontiers in neurology · 2022Article
- Parents'/caregivers' fears and concerns about their child's epilepsy: A scoping review.PloS one · 2022Article
- Development of a core outcome set for the orthopaedic management of spinal dysraphism : a study protocol.Bone & joint open · 2022Article
- Clinical Trial Design for Disease-Modifying Therapies for Genetic Epilepsies.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Review
- Development of a core outcome set for idiopathic clubfoot management.Bone & joint open · 2021Article
Corrections and comments
- Erratum issuedCorrigendum.2019
Authors and funding
14 authors at 8 institutions in 1 country.
Funding
Abstract
objectiveEstablishing a core set of outcomes to be evaluated and reported in intervention trials aims to improve the usefulness of health research. There is no established core outcome set (COS) for childhood epilepsies. The aim of this study was to select a COS to be used in evaluative research of interventions for children with rolandic epilepsy (RE).
methodsWe followed guidance from the COMET (Core Outcome Measures in Effectiveness Trials) Initiative. First, we identified outcomes that had been measured in research through a systematic review. Second, young people with RE, parents, and professionals were invited to take part in a Delphi survey in which participants rated the importance of candidate outcomes. Last, a face-to-face meeting was convened to seek consensus on which outcomes were critical to include and to ratify the final COS.
resultsFrom 37 eligible papers in the review, we identified and included 48 candidate outcomes in the survey. We sent invitations to 165 people registered to take part in the survey; of these, 102 (62%) completed Round 1, and 80 (78%) completed Round 2 (three young people, 16 parents, 61 professionals). In Round 2 we included four additional outcomes suggested by participants in Round 1. The consensus meeting included two young people, four parents, and nine professionals who were eligible to vote and ratified the COS as 39 outcomes across 10 domains. SIGNIFICANCE: Our methodology was a proportionate and pragmatic approach toward producing a COS for evaluating research on interventions aiming to improve the health of children with RE.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.