Evidence map›Paper›PMID 31021028›Full record

ArticleJournal of clinical laboratory analysis2019

Comparison of droplet digital PCR and direct Sanger sequencing for the detection of the BRAF

Zhuo Wang, Kejing Sun, Changwen Jing, Haixia Cao, Rong Ma, Jianzhong Wu

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 29 citations in OpenAlex.

  1. Detection ofBiomolecules · 2021
    Trial
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  4. Review
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  7. Somatic Activating ESR1 Mutation in an Aggressive Prolactinoma.The Journal of clinical endocrinology and metabolism · 2025
    Article
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  11. Review
  12. Article
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  18. Evaluating H3F3A K27M and G34R/V somatic mutations in a cohort of pediatric brain tumors of different and rare histologies.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  19. VE1 immunohistochemistry is an adjunct tool for detection of BRAFJournal of clinical laboratory analysis · 2021
    Article
  20. Detection ofCells · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zhuo WangClinical Cancer Research Center, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0002-3920-4348
Kejing SunGenesmile Company, Nanjing, China.
Changwen JingClinical Cancer Research Center, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Haixia CaoClinical Cancer Research Center, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Rong MaClinical Cancer Research Center, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Jianzhong WuClinical Cancer Research Center, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Cancer Hospital · CNGenesys (United States) · US

Funding

Science Foundation of Jiangsu Province BE2016795
6 · The paper itself

Abstract

backgroundThe BRAF

methodsSamples from a total of 120 patients with PTC and 30 patients with benign nodular thyroid disease who underwent thyroid surgery were collected. The BRAF

resultsThe BRAF

conclusionsddPCR was a reliable, highly sensitive alternative method for the detection of the BRAF

Indexed as

AdolescentAdultAgedCarcinoma, PapillaryDNA Mutational AnalysisFemaleHumansMaleMiddle AgedPolymerase Chain ReactionProto-Oncogene Proteins B-rafSequence Analysis, DNAThyroid NeoplasmsYoung AdultBRAF protein, humanProto-Oncogene Proteins B-rafBRAFV600E mutationddPCRpapillary thyroid carcinomaSanger sequencing

Identifiers

PMID31021028
PMCPMC6642310
OpenAlexW2941383663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.