Evidence map›Paper›PMID 31020920›Full record

ArticleTissue engineering. Part A2019

Skeletogenic Capacity of Human Perivascular Stem Cells Obtained Via Magnetic-Activated Cell Sorting.

Carolyn A Meyers, Jiajia Xu, Leititia Zhang, Leslie Chang, Yiyun Wang, Greg Asatrian, Catherine Ding, Noah Yan, Erin Zou, Kristen Broderick and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering. Part A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Five Decades Later, Are Mesenchymal Stem Cells Still Relevant?Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Carolyn A MeyersDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Jiajia XuDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Leititia ZhangDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Leslie ChangDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Yiyun WangDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Greg AsatrianUCLA and Orthopaedic Hospital Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, Los Angeles, California.
Catherine DingUCLA and Orthopaedic Hospital Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, Los Angeles, California.
Noah YanDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Erin ZouDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Kristen BroderickDepartment of Surgery, Johns Hopkins University, Baltimore, Maryland.
Min LeeSchool of Dentistry, University of California, Los Angeles, California.
Bruno PeaultUCLA and Orthopaedic Hospital Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, Los Angeles, California.
Aaron W JamesDepartment of Pathology, Johns Hopkins University, Baltimore, Maryland.
Johns Hopkins University · USOrthopaedic Hospital · USChina Medical University · CNUniversity of California, Los Angeles · USUniversity of Edinburgh · GB

Funding

Direct and indirect contributions of perivascular stem cells to bone healingR01AR070773 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI JAMES, AARON W · 2017 to 2021
$1.4M
Zeiss LSM780 Confocal Microscope for a Core FacilityS10OD016374 · OD · JOHNS HOPKINS UNIVERSITY · PI KUO, SCOT CHARLES · 2013 to 2013
$584k
NELL-1 isoforms for the systemic treatment of osteoporosisK08AR068316 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JAMES, AARON W · 2015 to 2019
$534k
Role of sensory nerves in cranial bone repairR21DE027922 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI CLEMENS, THOMAS L, JAMES, AARON W · 2018 to 2019
$450k
Medical Research Council G1000816NIAMS NIH HHS K08 AR068316NIAMS NIH HHS R01 AR070773NIDCR NIH HHS R21 DE027922NIH HHS S10 OD016374
6 · The paper itself

Abstract

Human perivascular stem/stromal cells (PSC) are a multipotent mesenchymal progenitor cell population defined by their perivascular residence. PSC are increasingly studied for their application in skeletal regenerative medicine. PSC from subcutaneous white adipose tissue are most commonly isolated via fluorescence-activated cell sorting (FACS), and defined as a bipartite population of CD146

Indexed as

Magnetic PhenomenaAdipose TissueAdultAntigens, CD34BiomarkersCell DifferentiationCell LineageCell SeparationHumansOsteogenesisSkullStem CellsWound HealingAntigens, CD34Biomarkersbone regenerationbone tissue engineeringMACSmagnetic activated cell sortingmesenchymal stem cellmesenchymal stromal cell

Identifiers

PMID31020920
PMCPMC6919244
OpenAlexW2987276588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.