Evidence map›Paper›PMID 31020891›Full record

ArticleThe Journal of international medical research2019

Combination of radiofrequency ablation and transcatheter arterial chemoembolization to treat hepatocellular carcinoma: measurement of distance from needle tip to nodule for assessment of local tumor progression.

Wang Haochen, Wang Jian, Song Li, Lv Tianshi, Tong Xiaoqiang, Zou Yinghua

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wang HaochenDepartment of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, China.
Wang JianDepartment of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-7653-9577
Song LiDepartment of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, China.
Lv TianshiDepartment of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, China.
Tong XiaoqiangDepartment of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, China.
Zou YinghuaDepartment of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, China.
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was performed to determine the relationship between the minimum distance from the radiofrequency ablation (RFA) needle tip to the tumor and local tumor progression (LTP) of hepatocellular carcinoma (HCC) nodules and identify prognostic factors for LTP.

methodsWe reviewed 197 patients (197 nodules) who underwent RFA after transcatheter arterial chemoembolization for HCC from January 2010 to January 2015. Three-dimensional registration of images was used to calculate the minimum distance from the tip to the tumor. We then divided the minimum distance into two groups: <2 and ≥2 mm. Contrast-enhanced computed tomography was performed after treatment. The LTP rate was calculated 1 and 3 years after RFA. We performed multivariate analysis to identify independent prognostic factors for LTP.

resultsThe cumulative 1-year LTP rates in the <2- and ≥2-mm groups were 82.7% and 4.3%, respectively, and the cumulative 3-year LTP rates in the two groups were 94.8% and 10.8%, respectively. The minimum distance from the needle tip to the tumor was an independent prognostic factor for LTP.

conclusionsA minimum distance of 2 mm from the needle tip to the tumor should be completely ablated along with the tumor.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsCarcinoma, HepatocellularChemoembolization, TherapeuticCombined Modality TherapyDisease ProgressionFemaleFollow-Up StudiesHumansLiver NeoplasmsMaleMiddle AgedNeedlesRadiofrequency AblationRetrospective StudiesTreatment Outcomehepatocellular carcinomalocal tumor progressionmarginprognostic factorradiofrequency ablationTranscatheter arterial chemoembolization

Identifiers

PMID31020891
PMCPMC6567703
OpenAlexW2941498223

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.