Evidence map›Paper›PMID 31020874›Full record

ArticleInternational journal of immunopathology and pharmacology

Beyond appearance: An unusual manifestation of isolated oral secondary syphilis.

Elena Mari, Maurizio Nudo, Enzo Palese, Luisa Cotticelli, Ciro Cotticelli, Grazia Zino, Rosa Coppola, Federica Maria Di Lella, Gabriele Arcari, Donatella Maria Rodio and 4 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Oral manifestations of syphilis: A report of six cases.Journal of clinical and experimental dentistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Elena Mari1 Division of Dermatology, IDI-IRCCS-FLMM, Rome, Italy.
Maurizio Nudo1 Division of Dermatology, IDI-IRCCS-FLMM, Rome, Italy.
Enzo Palese1 Division of Dermatology, IDI-IRCCS-FLMM, Rome, Italy.
Luisa Cotticelli2 Department of Oral and Maxillo Facial Sciences, University of Rome "La Sapienza," Rome, Italy.
Ciro Cotticelli2 Department of Oral and Maxillo Facial Sciences, University of Rome "La Sapienza," Rome, Italy.
Grazia Zino1 Division of Dermatology, IDI-IRCCS-FLMM, Rome, Italy.
Rosa Coppola3 Plastic and Reconstructive Surgery Unit, Campus Bio-Medico University of Rome, Rome, Italy.
Federica Maria Di Lella4 Department of Experimental Medicine, University of Campania "Luigi Vanvitelli," Naples, Italy.
Gabriele Arcari5 Department of Public Health and Infectious Diseases, University of Rome "La Sapienza," Rome, Italy.
Donatella Maria Rodio5 Department of Public Health and Infectious Diseases, University of Rome "La Sapienza," Rome, Italy.
Carla Prezioso5 Department of Public Health and Infectious Diseases, University of Rome "La Sapienza," Rome, Italy.
Valeria Pietropaolo5 Department of Public Health and Infectious Diseases, University of Rome "La Sapienza," Rome, Italy.ORCID https://orcid.org/0000-0001-5723-8886
Valeria Devirgiliis3 Plastic and Reconstructive Surgery Unit, Campus Bio-Medico University of Rome, Rome, Italy.
Vincenzo Panasiti3 Plastic and Reconstructive Surgery Unit, Campus Bio-Medico University of Rome, Rome, Italy.
Sapienza University of Rome · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversità Campus Bio-Medico · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syphilis is a sexually acquired chronic infection caused by Treponema pallidum and is characterized by a variety of clinical manifestations. The secondary stage of the disease results from the hematogenous and lymphatic dissemination of treponemes after a few weeks or months, and it is characterized by recurrent activity of the disease, with muco-cutaneous as well as systemic manifestations. Mucosal lesions range from small, superficial ulcers that resemble painless aphthae to large gray plaques, and they are generally associated with systemic manifestations of the disease. The exclusive asymptomatic oral localization not associated with general manifestations is uncommon but may actually be unrecognized and under-reported. We report a case of isolated oral manifestation as the unique presentation of secondary syphilis.

Indexed as

Anti-Bacterial AgentsFemaleHumansMiddle AgedPenicillin G BenzathineSyphilisAnti-Bacterial AgentsPenicillin G Benzathineoral syphilissecondary syphilisunusual manifestation

Identifiers

PMID31020874
PMCPMC6484239
OpenAlexW2941892669

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.