ArticleMagnetic resonance in medicine2019
Assessing test-retest reliability of phase contrast MRI for measuring cerebrospinal fluid and cerebral blood flow dynamics.
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 52 citations in OpenAlex.
- Rapid Tissue-CSF Water Exchange in the Human Brain Revealed by Magnetization Transfer Indirect Spin Labeling.Magnetic resonance in medicine · 2026Article
- Cerebral hemodynamics in early adolescents with congenital heart disease after infant open-heart surgery.Pediatric research · 2026Article
- Leptomeninges: Anatomy, Mechanisms of Disease and Neuroimaging.Neurology international · 2025Review
- Editorial: Cerebrospinal fluid flow imaging in Chiari Malformation type 1.Acta neurochirurgica · 2025Article
- Synchronous quantification of arterial, venous, and cerebrospinal fluid flow dynamics using real-time phase-contrast MRI.Fluids and barriers of the CNS · 2025Article
- AI-Augmented Quantitative MRI Predicts Spontaneous Intracranial Hypotension.Diagnostics (Basel, Switzerland) · 2025Article
- Patterns of pathological tau deposition reflect the dynamics of cortical brain activity.Cell reports · 2025Article
- Cerebrospinal fluid flow within ventricles and subarachnoid space evaluated by velocity selective spin labeling MRI.NeuroImage · 2025Article
- Individualized retrograde endoscopic transoccipital-fourth ventricular-midbrain aqueduct to third and lateral ventriculoperitoneal shunt for complex multilocular hydrocephalus with isolated fourth ventricle: a case report.Frontiers in medicine · 2025Article
- Simultaneous and synchronous characterization of blood and CSF flow dynamics using multiple Venc PC MRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Imputation models and error analysis for phase contrast MR cerebral blood flow measurements in heterogeneous pediatric and adult populations.Frontiers in physiology · 2025Article
- Quantifying CSF Dynamics disruption in idiopathic normal pressure hydrocephalus using phase lag between transmantle pressure and volumetric flow rate.Brain multiphysics · 2024Article
- Phase-contrast MRI analysis of cerebral blood and CSF flow dynamic interactions.Fluids and barriers of the CNS · 2024Article
- CSF dynamics throughout the ventricular system using 4D flow MRI: associations to arterial pulsatility, ventricular volumes, and age.Fluids and barriers of the CNS · 2024Article
- Texture-based morphometry in relation to apolipoprotein ε4 genotype, ageing and sex in a midlife population.Human brain mapping · 2024Article
- Decoding pulsatile patterns of cerebrospinal fluid dynamics through enhancing interpretability in machine learning.Scientific reports · 2024Article
- Four-dimensional flow MRI for quantitative assessment of cerebrospinal fluid dynamics: Status and opportunities.NMR in biomedicine · 2024Review
- Multimodal assessment of brain fluid clearance is associated with amyloid-beta deposition in humans.Journal of neuroradiology = Journal de neuroradiologie · 2024Article
- The impact of body position on neurofluid dynamics: present insights and advancements in imaging.Frontiers in aging neuroscience · 2024Review
- Cerebrospinal Fluid Flow in Patients with Huntington's Disease.Annals of neurology · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purposePathological states occur when cerebrospinal fluid (CSF) and cerebral blood flow (CBF) dynamics become dysregulated in the brain. Phase-contrast MRI (PC-MRI) is a noninvasive imaging technique that enables quantitative measurements of CSF and CBF flow. While studies have validated PC-MRI as an imaging technique for flow, few studies have evaluated its reliability for CSF and CBF flow parameters commonly associated with neurological disease. The purpose of this study was to evaluate test-retest reliability at the cerebral aqueduct (CA) and C2-C3 area using PC-MRI to assess the feasibility of investigating CSF and CBF flow dynamics.
methodsThis study was performed on 27 cognitively normal young adults (ages 20-35 years). Flow data was acquired on a 3T Siemens Prisma using a 2D cine-PC pulse sequence. Three consecutive flow measurements were acquired at the CA and C2-C3 area. Intraclass correlation coefficient (ICC) and coefficient of variance (CV) were used to evaluate intrarater, inter-rater, and test-retest reliability.
resultsAmong the 26 flow parameters analyzed, 22 had excellent reliability (ICC > 0.80), including measurements of CSF stroke volume, flush peak, and fill peak, and 4 parameters had good reliability (ICC 0.60-0.79). 16 flow parameters had a mean CV ≤ 10%, 7 had a CV ≤ 15%, and 3 had a CV ≤ 30%. All CSF and CBF flow measurements had excellent inter-rater and intrarater reliability (ICC > 0.80).
conclusionThis study shows that CSF and CBF flow can be reliably measured at the CA and C2-C3 area using PC-MRI, making it a promising tool for studying flow dynamics in the central nervous system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.