Evidence map›Paper›PMID 31020679›Full record

ArticlePsychophysiology2019

Lower resting cardiac autonomic balance in young adults with current major depression.

Christopher J Brush, Ryan L Olson, Peter J Ehmann, Anthony J Bocchine, Marsha E Bates, Jennifer F Buckman, Teresa M Leyro, Brandon L Alderman

Abstract read
In one paragraph

Article in Psychophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  5. Is autonomic functioning distinctly associated with anxiety and unsociability in preschoolers?International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2024
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christopher J BrushDepartment of Kinesiology and Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey.ORCID 0000-0002-8622-2610
Ryan L OlsonDepartment of Kinesiology, Health Promotion, and Recreation, University of North Texas, Denton, Texas.
Peter J EhmannDepartment of Kinesiology and Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Anthony J BocchineDepartment of Kinesiology and Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Marsha E BatesDepartment of Kinesiology and Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Jennifer F BuckmanDepartment of Kinesiology and Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Teresa M LeyroDepartment of Psychology, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Brandon L AldermanDepartment of Kinesiology and Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey.ORCID 0000-0003-0101-6533

Funding

Project IMPACT: In-the-Moment Protection from Automatic Capture by TriggersR01AA023667 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI BATES, MARSHA E., BUCKMAN, JENNIFER F. · 2015 to 2019
$2.7M
THE BAROREFLEX MECHANISM: TRANSLATION TO AUD TREATMENT AND PROGNOSTIC MODELSK24AA021778 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI BATES, MARSHA E. · 2013 to 2017
$830k
Deconstructing the temporal and multi-level influences of the baroreflex mechanism on alcohol use behaviorsK02AA025123 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI BUCKMAN, JENNIFER F. · 2017 to 2021
$762k
Development and Pilot Investigation of Heart Rate Variability Biofeedback for Smoking CessationR34DA043751 · NIDA · RUTGERS, THE STATE UNIV OF N.J. · PI LEYRO, TERESA MARIA · 2018 to 2020
$698k
NIAAA NIH HHS K02 AA025123NIAAA NIH HHS K02AA025123NIAAA NIH HHS K24 AA021778NIAAA NIH HHS K24AA021778NIAAA NIH HHS R01 AA023667NIDA NIH HHS R34 DA043751NIDA NIH HHS R34DA043751
6 · The paper itself

Abstract

Research on cardiac autonomic function in major depressive disorder (MDD) has predominantly examined cardiac vagal control and adopted a model of reciprocal autonomic balance. A proposed bivariate autonomic continuum uses cardiac autonomic balance (CAB) and cardiac autonomic regulation (CAR) models, derived from normalized values of respiratory sinus arrhythmia and pre-ejection period, to more adequately index patterns of autonomic control. The purpose of this study was to assess resting levels of CAB and CAR among young adults with and without a current diagnosis of major depression. One hundred forty-two young adults (n = 65 MDD, n = 77 healthy controls; 20.8 ± 2.6 years) completed a structured diagnostic interview, cardiovascular assessment, and a maximal aerobic fitness test. The findings revealed that CAB, but not CAR, significantly predicted current MDD status (OR = 0.70, 95% CI [0.53, 0.93]), an effect that remained after controlling for aerobic fitness and body mass index. Although CAB was found to be a significant predictor of current MDD status among a sample of young adults, there remained substantial variation in autonomic control that was not captured by the traditional model of reciprocal autonomic balance.

Indexed as

AdultAutonomic Nervous SystemCardiorespiratory FitnessElectrocardiographyFemaleHeartHeart RateHumansMajor Depressive DisorderMaleRetrospective StudiesYoung Adultautonomic nervous systemcardiac autonomic balancedepressionphysical health

Identifiers

PMID31020679
PMCPMC6650364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.