Evidence map›Paper›PMID 31020551›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

tRNAscan-SE: Searching for tRNA Genes in Genomic Sequences.

Patricia P Chan, Todd M Lowe

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,218 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,218citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,218 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. The halophilic archaeonMicrobiology spectrum · 2026
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  19. Review
  20. Article

1,158 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patricia P ChanDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, USA.
Todd M LoweDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, USA. tmjlowe@ucsc.edu.

Funding

A Unified Atlas of Dynamic tRNA FunctionR01HG006753 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI LOWE, TODD MICHAEL · 2012 to 2022
$4.6M
NHGRI NIH HHS R01 HG006753
6 · The paper itself

Abstract

Transfer RNAs are the largest, most complex non-coding RNA family, universal to all living organisms. tRNAscan-SE has been the de facto tool for predicting tRNA genes in whole genomes. The newly developed version 2.0 has incorporated advanced methodologies with improved probabilistic search software and a suite of new gene models, enabling better functional classification of predicted genes. This chapter describes the use of the UNIX command-driven and online web versions, illustrating different search modes and options.

Indexed as

SoftwareDatabases, GeneticData DisplayEukaryotic CellsGenomicsInternetModels, GeneticRNA, TransferRNA, TransferCovariance modelGene predictionNon-coding RNARNA secondary structureTransfer RNA

Identifiers

PMID31020551
PMCPMC6768409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.