Evidence map›Paper›PMID 31020475›Full record

ArticleClinical rheumatology2019

Neck circumference is associated with hyperuricemia: a cross-sectional study.

Xiuhua Shen, Shouling Wu, Renying Xu, Yuntao Wu, Junjuan Li, Liufu Cui, Rong Shu, Xiang Gao

Abstract read
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In one paragraph

Article in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiuhua ShenDepartment of Clinical Nutrition, Shanghai Xin Hua Hospital, Shanghai, China.
Shouling WuDepartment of Cardiology, Kailuan General Hospital, No. 57 Xinhua Road (East), Tangshan, 063000, China. drwusl@163.com.
Renying XuDepartment of Clinical Nutrition, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yuntao WuDepartment of Cardiology, Kailuan General Hospital, No. 57 Xinhua Road (East), Tangshan, 063000, China.
Junjuan LiDepartment of Nephrology, Kailuan General Hospital, Tangshan, China.
Liufu CuiDepartment of Rheumatology, Kailuan General Hospital, Tangshan, China.
Rong ShuDepartment of Rheumatology, Kailuan General Hospital, Tangshan, China.
Xiang GaoDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, PA, 16802, USA. xxg14@psu.edu.ORCID http://orcid.org/0000-0003-2617-6509

Funding

National Natural Science Foundation of China 81773407Natural Science Foundation of Shanghai 17ZR1415700
6 · The paper itself

Abstract

BACKGROUND/

objectiveNeck circumference (NC) is associated with metabolic abnormalities, independent of other obesity indices. However, data are limited regarding the potential relation between NC and serum uric acid (UA) concentrations. Therefore, we evaluated the cross-sectional association between NC and UA concentration, and odds of having hyperuricemia in a community-based cohort. SUBJECTS AND

methodsThe current study included 87,782 participants (16,317 women and 71,465 men, 52.2 ± 14.1 y) of the Kailuan Study. NC and UA concentration were measured in 2014. We used generalized linear model to investigate the association between NC and serum UA concentration and logistic regression model to investigate the association between NC and likelihood of having hyperuricemia (≥ 7 mg/dl in men and ≥ 6 mg/dl in women), adjusting for demographic factor, anthropometric indices, plasma lipid profiles, blood glucose, blood pressure, physical exercise, snoring, smoking, diet quality, and alcohol consumption.

resultsHigher NC was associated with higher serum UA concentration, and higher odds of hyperuricemia in both men and women after adjusting for potential confounders (both p < 0.001). Each additional 5-cm increase in NC was associated with 6% higher likelihood of having hyperuricemia (adjusted OR = 1.06; 95% CI 1.02, 1.1) in men and 17% in women (adjusted OR = 1.17; 95% CI 1.06, 1.28) (p interaction = 0.01). Similar pattern was observed after excluding participants who reported use of anti-hypertensive drugs, participants with obesity or higher waist circumference, and participants with history of gout and chronic kidney diseases.

conclusionsHigher NC was associated with higher serum UA concentration and higher risk of hyperuricemia in Chinese adult population. CLINICAL TRIAL NUMBER: Kailuan Study (ChiCTR-TNRC-11001489).

Indexed as

AdultAgedAnthropometryBody Mass IndexCross-Sectional StudiesFemaleHumansHyperuricemiaMaleMiddle AgedNeckUric AcidWaist CircumferenceUric AcidHyperuricemiaNeck circumferenceSerum uric acid

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.