ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020
Radiotherapy impairs adhesive bonding in permanent teeth.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 53 citations in OpenAlex.
- Push-out bond strength of fiber posts to irradiated and non-irradiated intraradicular dentin.Clinical oral investigations · 2022Trial
- Protective and remineralizing capacity of biosilicate, chitosan-based material, and fluoride on demineralized and irradiated enamel.Radiation and environmental biophysics · 2026Article
- Clinically relevant radiation therapy doses and obturation techniques modulate the adhesive performance of a resin-based sealer: interfacial integrity and bond strength analyses.Clinical oral investigations · 2026Article
- The Effect of Radiotherapy on the Microtensile Bond Strength of Dentin in Relation to the Timing of Restoration Procedure.International journal of dentistry · 2026Article
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- Microshear bond strength of conventional and bioactive restorative materials to irradiated and non-irradiated dentin: an in vitro study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Role of diode laser (810 nm) and/or fluoride varnish for the treatment of gamma-irradiated hypersensitive human dentin (An in vitro study).Scientific reports · 2025Article
- Article
- Effects of radiation therapy on the morphology and composition of root dentin and cementum in primary teeth.Brazilian oral research · 2025Article
- Impact of gamma radiation on marginal adaptation of nanohybrid composite and composition of dental hard tissues - Scanning electron microscopy and X-ray diffraction analysis: AnJournal of conservative dentistry and endodontics · 2024Article
- Effect of ionizing radiation on the shear bond strength of two different adhesive systems in primary teeth. in-vitro study.BMC oral health · 2024Article
- Effect of different approaches of direct radiation on the surface structure and caries susceptibility of enamel.Scientific reports · 2024Article
- Acid challenge exacerbates activation of matrix metalloproteinases in permanent teeth undergoing radiotherapy.Brazilian oral research · 2024Article
- Impact of Irradiation on the Adhesive Performance of Resin-Based Dental Biomaterials: A Systematic Review of Laboratory Studies.Materials (Basel, Switzerland) · 2023Review
- Color stability and microhardness alteration of irradiated dental enamel treated with a high fluoride concentration toothpaste.Clinical oral investigations · 2022Article
- Activation of gelatinases in permanent human teeth after different experimental radiotherapy protocols.Brazilian dental journalArticle
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the in vitro effects of radiotherapy (RT) on the morphological surface of the enamel and dentin and to determine the best adhesive system and most appropriate time to restore teeth in head and neck cancer patients.
methodsSixty third molars were cut into 120 enamel fragments and 120 dentin fragments and divided into four groups (n = 30): G1 (control): nonirradiated, only restorative procedure; G2: restorative procedure immediately before RT; G3: restorative procedure immediately after RT; and G4: restorative procedure 6 months after RT. Each group was divided into two subgroups: Adper™ Single Bond 2 (SB) and Clearfill SE Bond (CL) based on the material used. After RT and restorative procedures, the specimens were subjected to confocal microscopy and shear bond strength test. Data were analyzed using a two-way ANOVA followed by Tukey's test at a significance level of 5%.
resultsMorphological changes were observed in both substrates after a cumulative dose of 40 Gy, and after 60 Gy, the changes were more evident in both substrates. CL had the highest strength values in both substrates (p < 0.05), and G2 had the lowest strength values for the enamel and dentin (p < 0.05).
conclusionsBased on the in vitro study results, we can conclude that RT substantially changes the morphological surface of enamel and dentin and impairs the bond strength. The Clearfill system yielded better results than Adper Single Bond 2, and restoring teeth before RT resulted in the worst results in both substrates.
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