SynthesisSurgical endoscopy2019
Incidence and predictors of postoperative ileus after loop ileostomy closure: a systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Protective Role of Preoperative Stimulation of the Distal Limb of the Ileostomy Loop With GABA Before Ileostomy Closure
The STIMIC Trial: A Multicenter Randomized Control Trial Evaluating the Impact of Ambulatory Physiological Stimulation of the Efferent Limb Prior to Ileostomy Closure on Colorectal Microbiota Composition and Histopathological Findings
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Efferent limb stimulation prior to loop ileostomy closure: a systematic review and meta-analysis.Techniques in coloproctology · 2023Pooled it
- The ILEOSTIM trial: A multicentre randomised controlled trial evaluating the impact of efferent loop stimulation prior to ileostomy reversal on postoperative ileus.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Trial
- Bowel stimulation before loop ileostomy closure to reduce postoperative ileus: a multicenter, single-blinded, randomized controlled trial.Surgical endoscopy · 2023Trial
- Trial
- Morphological, Molecular and Motility Changes in Human Small Intestine After Loop Ileostomy.Journal of neurogastroenterology and motility · 2026Article
- Ileostoma as a promising tool in pathophysiological study and clinical intervention: a review from bench to beside.Frontiers in immunology · 2026Review
- A predictive tool for postoperative ileus after ileostomy closure: Model development and validation.Turkish journal of surgery · 2025Article
- The impact of delayed closure of ileostomy on postoperative complications in patients with Crohn's disease: a case-matched study.Updates in surgery · 2024Article
- Defining the safety of early ileostomy closure after ileal pouch anal anastomosis.Techniques in coloproctology · 2023Article
- ILEOSTIM trial: a study protocol to evaluate the effectiveness of efferent loop stimulation before ileostomy reversal.Techniques in coloproctology · 2023Article
- Short-term outcome of diverting loop ileostomy reversals performed by residents: a retrospective cohort prognostic factor study.International journal of colorectal disease · 2023Article
- Cost of postoperative ileus following colorectal surgery: A cost analysis in the Australian public hospital setting.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Article
- Can physiological stimulation prior to ileostomy closure reduce postoperative ileus? A prospective multicenter pilot study.Techniques in coloproctology · 2022Article
- Ostomy closure rate during COVID-19 pandemic: an Italian multicentre observational study.Updates in surgery · 2022Observational
- Self-administered succus entericus reinfusion before ileostomy closure improves short-term outcomes.BMC surgery · 2021Article
- Impact of timing of reversal of loop ileostomy on patient outcomes: a retrospective cohort study.Techniques in coloproctology · 2021Article
- A nomogram to predict risk factors of frequent defecation early after ileostomy reversal for rectal cancer patients.Annals of translational medicine · 2021Article
- Early postoperative outcomes of diverting loop ileostomy closure surgery following laparoscopic versus open colorectal surgery.Surgical endoscopy · 2021Article
- Diversion Colitis and Probiotic Stimulation: Effects of Bowel Stimulation Prior to Ileostomy Closure.Frontiers in medicine · 2021Article
- Short-Term and Long-Term Outcomes in Mid and Low Rectal Cancer With Robotic Surgery.Frontiers in oncology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
introductionPostoperative ileus (POI) is regarded as the most clinically significant morbidity following loop ileostomy closure; however, its incidence remains poorly understood. Our objective was therefore to determine the pooled incidence of POI after loop ileostomy closure and identify risk factors associated with its development.
methodsWe systematically searched MEDLINE (via Ovid and PubMed), Embase, the Cochrane Library, Biosis Previews, and Scopus to identify studies reporting the incidence of POI in patients who underwent loop ileostomy closure. Two independent reviewers extracted data and appraised study quality. Cumulative incidence proportions were pooled across studies using a random-effects meta-analytic model.
resultsSixty-seven studies, including 9528 patients, met our inclusion criteria. The pooled estimate of POI was 8.0% (95% CI 6.9-9.3%; I
conclusionsPOI is an important complication after loop ileostomy closure, and its incidence is dependent on its definition. More research aimed at studying this complication is required to better understand risk factors for POI after loop ileostomy closure.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.