ArticleEuropean heart journal. Case reports2018
A case report of Löffler endocarditis in idiopathic hypereosinophilic syndrome: recovery is possible.
Article in European heart journal. Case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Four challenging cases of eosinophilic endocarditis or myocarditis with literature review.Journal of cardiothoracic surgery · 2025Review
- A case report of Löffler's endocarditis with right ventricular outflow obstruction in idiopathic hypereosinophilic syndrome: timely surgical intervention is crucial.European heart journal. Case reports · 2024Article
- Hypereosinophilic Syndrome with Advanced-Stage Loeffler Endocarditis.CASE (Philadelphia, Pa.) · 2022Article
- Successful Treatment of Classical Loeffler's Endocarditis.Journal of cardiovascular imaging · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
introductionHypereosinophilic syndrome (HES) is a myeloproliferative disorder characterized by persistent eosinophilia that is associated with damage to multiple organs. CASE PRESENTATION: Herein, we describe a case of left ventricular (LV) Löffler endocarditis on top of idiopathic HES leading to inflow and outflow obstruction. The posterior mitral leaflet was involved in the fibrotic process leading to severe mitral valve regurgitation. There was a mural thrombus in the left ventricle, which resulted in thrombo-embolic complications in the form of lower limb ischaemia. The patient was treated with high-dose corticosteroids and anticoagulants with significant improvement of his cardiac condition. DISCUSSION: In patients with persistent hypereosinophilia, thorough workup is recommended to identify any possible primary cause and detect associated end-organ damage. Treatment should be started as early as possible after establishing the diagnosis to reduce morbidity and prevent complications. Corticosteroids are the first-line therapy that usually cause a rapid reduction in the level of the eosinophilia and must be started promptly if cardiac involvement is present to attain rapid reduction in the eosinophil level and reverse the cardiac damage.
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