Evidence map›Paper›PMID 31020002›Full record

Trial reportAnnals of clinical and translational neurology2019

Effect of Tui Na on upper limb spasticity after stroke: a randomized clinical trial.

Meng Wang, Shouguo Liu, Zhihang Peng, Yi Zhu, Xiaodong Feng, Yihuang Gu, Jianhua Sun, Qiang Tang, Hongxia Chen, Xiaolin Huang and 11 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of clinical and translational neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Efficacy and safety of tolperisone versus baclofen among Chinese patients with spasticity associated with spinal cord injury: a non-randomized retrospective study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 16 institutions in 1 country.

Meng WangThe Rehabilitation Medicine Department The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu China.
Shouguo LiuThe Rehabilitation Medicine Department The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu China.
Zhihang PengThe Teaching and Research Department of Statistics Nanjing Medical University Nanjing Jiangsu China.
Yi ZhuRehabilitation Center The Second Affiliated Hospital of HaiNan Medical University Haikou Hainan China.
Xiaodong FengThe Rehabilitation Department The First Affiliated Hospital of Henan University of Traditional Chinese Medicine Zhengzhou Henan China.
Yihuang GuThe Second Clinical Medical School Nanjing University of Chinese Medicine Nanjing Jiangsu China.
Jianhua SunThe Acupuncture Rehabilitation Department Jiangsu Province Hospital of Traditional Chinese Medicine Nanjing Jiangsu China.
Qiang TangRehabilitation Center The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine Haerbin Heilongjiang China.
Hongxia ChenThe Rehabilitation Department Guangdong Provincial Traditional Chinese Medicine Hospital Guangdong China.
Xiaolin HuangThe Rehabilitation Department Tongji Medical College Huazhong University of science & Technology Wuhan Hubei China.
Jun HuThe Neurological Rehabilitation Department Shanghai University of Traditional Chinese Medicine Shanghai China.
Wei ChenRehabilitation Center Xuzhou Central Hospital Xuzhou Jiangsu China.
Jie XiangThe Rehabilitation Department The Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu China.
Chunxiao WanThe Rehabilitation Department Tianjin Medical University General Hospital Tianjin China.
Gangqi FanThe Neurology Department Nanjing Hospital of Traditional Chinese Medicine Nanjing Jiangsu China.
Jianhu LuThe Neurology Department Nanjing Hospital of Traditional Chinese Medicine Nanjing Jiangsu China.
Wenguang XiaThe Rehabilitation Department Hubei Provincial Hospital of Integrated Chinese & Western Medicine Wuhan Hubei China.
Liping ChenThe Rehabilitation Department Lianyungang Chinese Medicine Hospital Lianyungang China.
Lihua WangThe Rehabilitation Department Dongguan Kanghua Hospital Dongguan China.
Xiao LuThe Rehabilitation Medicine Department The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu China.
Jianan LiThe Rehabilitation Medicine Department The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu China.
Jiangsu Province Hospital · CNNanjing Medical University · CNNanjing Traditional Chinese Medicine Hospital · CNFirst Affiliated Hospital of Heilongjiang University of Chinese Medicine · CNFirst Affiliated Hospital of Henan University of Traditional Chinese Medicine · CNGuangdong Provincial Hospital of Traditional Chinese Medicine · CNGuhua Hospital · CNHainan Medical University · CNHuazhong University of Science and Technology · CNIntegrated Chinese Medicine (China) · CNSecond Affiliated Hospital of Nanjing Medical University · CNShanghai University of Traditional Chinese Medicine · CNThe First People’s Hospital of Lianyungang · CNTianjin Medical University General Hospital · CNXuzhou Central Hospital · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the efficacy and safety of Tui Na for treating spasticity of the upper limbs of stroke patients.

designA prospective, multicenter, blinded, randomized controlled intervention study. SUBJECTS: Stroke patients with upper limb spasticity who were treated between December 2013 and February 2017 in 16 participating institutions in China were randomly assigned to receive either Tui Na plus conventional rehabilitation (Tui Na group,

methodsEligible adult patients (aged 18-75 years) were enrolled 1-12 months after stroke and randomly allocated in a 1:1 ratio to the two groups. Outcome assessors were blinded to treatment allocation. Muscle tone in the spastic muscles was evaluated using the Modified Ashworth Scale (MAS), and the primary endpoint was the change in MAS score over 4 weeks of treatment.

resultsAmong patients who had experienced stroke 1-3 months before treatment, the Tui Na group experienced significantly greater reductions in MAS scores for three muscle groups than did the control group after 4 weeks of treatment. These improvements were sustained at the 3- and 6-month follow-ups. However, among patients who suffered from stroke 4-6 months and 7-12 months before treatment, the change in MAS with treatment did not differ significantly between those who did and those who did not receive Tui Na. No Tui Na-related adverse events during treatment were reported the groups.

conclusionTui Na was effective and safe for alleviating poststroke spasticity within 1-3 months after stroke onset.

Indexed as

Stroke RehabilitationAdolescentAdultAgedBotulinum Toxins, Type ADouble-Blind MethodFemaleHumansMaleMiddle AgedMuscle SpasticityNeuromuscular AgentsOutcome Assessment, Health CareProspective StudiesStrokeTreatment OutcomeBotulinum Toxins, Type ANeuromuscular Agents

Identifiers

PMID31020002
PMCPMC6469238
OpenAlexW2924430187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.