Evidence map›Paper›PMID 31020000›Full record

ArticleAnnals of clinical and translational neurology2019

Predictors of successful endovascular treatment in severe cerebral venous sinus thrombosis.

Xiaoxu Yang, Fang Wu, Yuehong Liu, Jiangang Duan, Ran Meng, Jian Chen, Debiao Li, Zhaoyang Fan, Marc Fisher, Qi Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 30 citations in OpenAlex.

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  5. Cerebral venous thrombosis: Current management, recent advances and future directions.International journal of stroke : official journal of the International Stroke Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Xiaoxu YangDepartment of Radiology Xuanwu Hospital Beijing China.
Fang WuDepartment of Radiology Xuanwu Hospital Beijing China.
Yuehong LiuDepartment of Radiology Xuanwu Hospital Beijing China.
Jiangang DuanDepartment of Emergency Xuanwu Hospital Beijing China.
Ran MengDepartment of Neurology Xuanwu Hospital Beijing China.
Jian ChenDepartment of Neurosurgery Xuanwu Hospital Beijing China.
Debiao LiBiomedical Imaging Research Institute Cedars Sinai Medical Center Los Angeles California.
Zhaoyang FanBiomedical Imaging Research Institute Cedars Sinai Medical Center Los Angeles California.
Marc FisherNeurology Beth Israel Deaconess Medical Center Boston Massachusetts.
Qi YangDepartment of Radiology Xuanwu Hospital Beijing China.ORCID https://orcid.org/0000-0002-5773-0456
Xunming JiDepartment of Neurosurgery Xuanwu Hospital Beijing China.
Beijing Xuanwu Traditional Chinese Medicine Hospital · CNCedars-Sinai Medical Center · USBeth Israel Deaconess Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study was to evaluate the thrombus characteristics affecting the extent of recanalization to identify patients with severe cerebral venous sinus thrombus (CVT) more likely to benefit from endovascular therapy.

methodsSevere CVT patients scheduled for endovascular treatment were prospectively recruited into the study. Each thrombosed venous segment was evaluated regarding complete or partial recanalization based on digital subtraction angiography (DSA) after treatment. Magnetic resonance black-blood thrombus imaging (MRBTI) was performed 1 day before endovascular treatment. The signal-to-noise ratio (SNR) of the clot, age of the clot, and baseline volume of the clot were compared between the complete and partial recanalization groups. A logistic regression analysis was performed to identify the association between these clot characteristics and recanalization status.

resultsTwenty-one CVT patients undergoing endovascular therapy were prospectively included. There were 110 thrombosed segments, 54 of these segments were completely recanalized after endovascular treatment. An acute clot sign (ACS) was found in 39 segments and a subacute clot sign (SCS) was found in 71 segments. There was no significant difference on baseline volume of the clot (1638.8 ± 1432.2 mm

interpretationACS can be used to predict complete recanalization in patients undergoing endovascular treatment. MRBTI provides a robust method to define clot composition and is potentially useful in selecting the most appropriate CVT patients for endovascular treatment.

Indexed as

AdultAngiography, Digital SubtractionCerebral AngiographyCerebral VeinsFemaleHumansIntracranial ThrombosisMagnetic Resonance AngiographyMaleSinus Thrombosis, IntracranialThrombolytic TherapyThrombosisTomography, X-Ray ComputedVenous Thrombosis

Identifiers

PMID31020000
PMCPMC6469256
OpenAlexW2921797668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.