Evidence map›Paper›PMID 31019995›Full record

ArticleAnnals of clinical and translational neurology2019

Toll-like receptor-4 299Gly allele is associated with Guillain-Barré syndrome in Bangladesh.

Israt Jahan, Rijwan U Ahammad, Mir M Khalid, Mohammad I Rahman, Shoma Hayat, Badrul Islam, Quazi D Mohammad, Zhahirul Islam

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Guillain Barre Syndrome as a Complication of COVID-19: A Systematic Review.The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2022
    Pooled it
  2. Review
  3. Guillain-Barré syndrome.Nature reviews. Disease primers · 2024
    Article
  4. Article
  5. Article
  6. Novel Immunological and Therapeutic Insights in Guillain-Barré Syndrome and CIDP.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Israt JahanLaboratory Sciences and Services Division icddr,b Dhaka Bangladesh.
Rijwan U AhammadLaboratory Sciences and Services Division icddr,b Dhaka Bangladesh.
Mir M KhalidLaboratory Sciences and Services Division icddr,b Dhaka Bangladesh.
Mohammad I RahmanLaboratory Sciences and Services Division icddr,b Dhaka Bangladesh.
Shoma HayatLaboratory Sciences and Services Division icddr,b Dhaka Bangladesh.
Badrul IslamLaboratory Sciences and Services Division icddr,b Dhaka Bangladesh.
Quazi D MohammadNational Institute of Neurosciences and Hospital Dhaka Bangladesh.
Zhahirul IslamLaboratory Sciences and Services Division icddr,b Dhaka Bangladesh.ORCID 0000-0003-0935-8079
International Centre for Diarrhoeal Disease Research · BDGladstone Institutes · USNational Institute of Neurosciences & Hospital · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTLR4 plays an important role in the pathogenesis of Guillain-Barré syndrome (GBS). The relationships between

methodsA total of 290 subjects were included in this study: 141 patients with GBS and 149 unrelated healthy controls. The

resultsThe minor 299Gly allele was significantly associated with GBS susceptibility (

interpretationThe

Indexed as

AdolescentAdultAgedAllelesBangladeshFemaleGene FrequencyGenotypeGuillain-Barre SyndromeHumansMaleMiddle AgedPolymorphism, Single NucleotideToll-Like Receptor 4Young AdultTLR4 protein, humanToll-Like Receptor 4

Identifiers

PMID31019995
PMCPMC6469239
OpenAlexW2919289418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.