ArticleAnnals of translational medicine2019
Risk factors associated with prolonged air leak after video-assisted thoracic surgery pulmonary resection: a predictive model and meta-analysis.
Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Prediction models for prolonged air leak after pulmonary surgery: a systematic review and critical appraisal.Frontiers in oncology · 2026Pooled it
- Does the Fissure Last Technique Really Reduce Postoperative Airleak After Lung Resection? Results From a Prospective Randomized Controlled Trial.Interdisciplinary cardiovascular and thoracic surgery · 2026Trial
- Long-term economic value analysis of reducing postoperative air leak following lung resection.Journal of thoracic disease · 2026Article
- From Alveolar Injury to Precision Perioperative Care: Integrating Molecular Biomarkers and Technology-Enabled Strategies for Prolonged Air Leak After Lung Resection.Mediators of inflammation · 2026Review
- Chest tube provocative clamping in patients having moderate or intense air leaks after lung resection to accelerate recovery.Journal of thoracic disease · 2024Article
- Incidence of air leaks in patients undergoing robotic thoracic surgery and video-assisted thoracic surgery.Nagoya journal of medical science · 2024Article
- Risk factor analysis and nomogram prediction model construction of postoperative complications of thoracoscopic non-small cell lung cancer.Journal of thoracic disease · 2024Article
- Outcomes of lung cancer surgery in patients with COVID-19 history: a single center cohort study.General thoracic and cardiovascular surgery · 2023Article
- Risk factors, complications and costs of prolonged air leak after video-assisted thoracoscopic surgery for primary lung cancer.Journal of thoracic disease · 2023Article
- Preoperative Omega-6/Omega-3 Fatty Acid Ratio Could Predict Postoperative Outcomes in Patients with Surgically Resected Non-Small-Cell Lung Cancer.Current oncology (Toronto, Ont.) · 2022Observational
- Air leaks: leave well enough alone.Journal of thoracic disease · 2022Article
- A nomogram for preoperative prediction of prolonged air leak after pulmonary malignancy resection.Translational lung cancer research · 2021Article
- Predictors of failure of intersegmental line creation using bronchoscopic jet ventilation for thoracoscopic pulmonary segmentectomy.JA clinical reports · 2021Article
- Clinical Outcomes And Cost-Effectiveness Of Different Staplers For Lung Lobectomy With Video-Assisted Thoracic Surgery.Cancer management and research · 2019Article
- AI-Assisted Volumetric Comparison of Parenchyma-Sparing Effect in Robotic Segmentectomy vs Lobectomy.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to establish a predictive model for prolonged air leak (PAL) after video-assisted thoracic surgery (VATS) lung resection; and additionally, to present a meta-analysis of the relevant literature to estimate the association between various clinical factors and PAL.
methodsA retrospective, case-control study was conducted using univariate analysis and logistic regression based on 493 medical records from patients who underwent VATS lung resection between January 2015 and August 2017 at our institution. PAL was defined as air leak more than 5 days after lung surgery. Subsequently, a nomogram was established as a predictive model. Relevant studies were screened from PubMed, Embase and Cochrane for relevant studies and data was extracted from those enrolled. Pooled odds ratios or weighted mean differences with corresponding 95% confidence intervals were calculated to estimate the association between various clinical factors and PAL.
resultsIncidence of PAL after VATS lung resection was observed in 54 (10.8%) of 493 patients. Logistic regression revealed that smoking (P=0.014), pulmonary function (P=0.011), pleural adhesion (P<0.001), stapling length (P<0.001), early postoperative drainage (P=0.002) were significantly associated with PAL. Our meta-analysis, including 17 eligible studies and 14 potential risk factors, further validating our findings. Upper lobectomy was determined to be a significant risk factor for PAL in Europeans and North Americans (OR =2.03, P<0.001), but not in Asians (OR =1.04, P=0.610). Importantly, the constructed nomogram demonstrated a good predictive ability (C-index =0.858).
conclusionsLung stapling length and early postoperative drainage are important indicators for the evaluation of PAL occurrence. Upper pulmonary resection is a factor with particular regional differences as its association with PAL is not significant within Asian populations. Our nomogram, incorporating multiple factors, provided a simple and practical predictive model with value for clinical application.
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