Evidence map›Paper›PMID 31019943›Full record

ArticleAnnals of translational medicine2019

Significant association of CD4

Xiaofan Yang, Weiwen Wang, Juan Xu, Ming-Shun Zhang, Huanping Mei, Youxuan Shen, Miao-Jia Zhang, Xiaohui Ji, Huijuan Wang

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Annals of medicine · 2024
    Article
  3. Current cell therapies for systemic lupus erythematosus.Stem cells translational medicine · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. New biomarkers in SLE: from bench to bedside.Rheumatology (Oxford, England) · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Non-Coding RNAs in CD4Frontiers in immunology · 2020
    Review
  13. Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xiaofan YangDepartment of Immunology, School of Basic Medical Science, Nanjing Medical University (NJMU), Nanjing 211166, China.
Weiwen WangNanjing First Hospital Affiliated to NJMU, Nanjing 210006, China.
Juan XuDepartment of Immunology, School of Basic Medical Science, Nanjing Medical University (NJMU), Nanjing 211166, China.
Ming-Shun ZhangDepartment of Immunology, School of Basic Medical Science, Nanjing Medical University (NJMU), Nanjing 211166, China.
Huanping MeiDepartment of Rheumatology, the First Affiliated Hospital of NJMU, Nanjing 210036, China.
Youxuan ShenDepartment of Rheumatology, the First Affiliated Hospital of NJMU, Nanjing 210036, China.
Miao-Jia ZhangDepartment of Rheumatology, the First Affiliated Hospital of NJMU, Nanjing 210036, China.
Xiaohui JiDepartment of Immunology, School of Basic Medical Science, Nanjing Medical University (NJMU), Nanjing 211166, China.
Huijuan WangDepartment of Immunology, School of Basic Medical Science, Nanjing Medical University (NJMU), Nanjing 211166, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegulatory T (Treg) cells are one of the important mechanisms in maintaining self-tolerance and immune homeostasis. CD4

methodsThe peripheral blood T cells (PBMCs) from patients with SLE and healthy controls were isolated, and followed by the isolation of CD3

resultsCD4

conclusionsThere is clear and definite evidence from the present study indicating the important role of CD4

Indexed as

cytokineFoxp3regulatory T cell (Treg)systemic lupus erythematosus (SLE)

Identifiers

PMID31019943
PMCPMC6462640
OpenAlexW2917032809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.